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Qiuzi Dai
Researcher at Tsinghua University
Publications - 2
Citations - 80
Qiuzi Dai is an academic researcher from Tsinghua University. The author has contributed to research in topics: Topoisomerase inhibitor & Poly (ADP-Ribose) Polymerase Inhibitor. The author has an hindex of 2, co-authored 2 publications receiving 54 citations.
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Journal ArticleDOI
Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy.
Zigao Yuan,Shaopeng Chen,Changjun Chen,Jiwei Chen,Chengken Chen,Qiuzi Dai,Chunmei Gao,Yuyang Jiang +7 more
TL;DR: It is suggested that single agents inhibiting Topo and PARP concurrently might be an alternative for cancer therapy and 11l represented a potential lead compound for development of antitumor agents.
Journal ArticleDOI
Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy.
Zigao Yuan,Shaopeng Chen,Chunmei Gao,Qiuzi Dai,Cunlong Zhang,Qinsheng Sun,Jin-Shun Lin,Chun Guo,Yu Zong Chen,Yuyang Jiang,Yuyang Jiang +10 more
TL;DR: The development of a novel dual DNMT and HDAC inhibitor C02S which showed potent enzymatic inhibitory activities against DNMT1, DNMT3A,DNMT3B andHDAC1 with IC50 values of 2.05, 0.93, 1.16 µM, respectively is reported.