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Quentin Greba
Researcher at University of Saskatchewan
Publications - 38
Citations - 725
Quentin Greba is an academic researcher from University of Saskatchewan. The author has contributed to research in topics: Prefrontal cortex & Working memory. The author has an hindex of 14, co-authored 33 publications receiving 516 citations.
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Journal ArticleDOI
Alterations in Reward, Fear and Safety Cue Discrimination after Inactivation of the Rat Prelimbic and Infralimbic Cortices
TL;DR: The data suggest that alterations in the balance of activity between areas homologous to the prelimbic and infralimbic cortices may be involved in the processes that go awry in anxiety and addiction disorders.
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Developmental disruption of perineuronal nets in the medial prefrontal cortex after maternal immune activation.
John W. Paylor,Brittney R. Lins,Quentin Greba,Nicholas Moen,Reiner Silveira de Moraes,John G. Howland,Ian R. Winship +6 more
TL;DR: The results indicate MIA causes region specific developmental abnormalities in PNNs in the PFC of offspring, confirming the polyI:C model replicates neuropathological alterations associated with schizophrenia and may identify novel mechanisms for cognitive and emotional dysfunction in the disorder.
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Behavioral alterations in rat offspring following maternal immune activation and ELR-CXC chemokine receptor antagonism during pregnancy: implications for neurodevelopmental psychiatric disorders.
Stephanie A. Ballendine,Quentin Greba,Wojciech Dawicki,Xiaobei Zhang,John R. Gordon,John G. Howland +5 more
TL;DR: While G31P did not completely reverse the behavioral impairments caused by polyI:C, it enhanced PPI during adolescence and strategy set-shifting and reversal learning during young adulthood, and these results suggest that while polyI:[C]C treatment significantly increases maternal CXCL1, elevations of this chemokine are not solely responsible for the effects of polyI;C on the behavior of the offspring.
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Prospective Analysis of the Effects of Maternal Immune Activation on Rat Cytokines during Pregnancy and Behavior of the Male Offspring Relevant to Schizophrenia.
Brittney R. Lins,Jessica L. Hurtubise,Andrew J. Roebuck,Wendie N. Marks,Nadine K. Zabder,Gavin A. Scott,Quentin Greba,Wojciech Dawicki,Xiaobei Zhang,Christopher D. Rudulier,John R. Gordon,John G. Howland +11 more
TL;DR: Overall, while the offspring of polyI:C-treated rats displayed behavior abnormalities, maternal serum cytokines were not related to the long-term behavior changes in the offspring.
Journal ArticleDOI
Chronic maternal hyperglycemia induced during mid-pregnancy in rats increases RAGE expression, augments hippocampal excitability, and alters behavior of the offspring.
TL;DR: It is suggested that chronic maternal hyperglycemia alters normal hippocampal development and behavior of the offspring, effects that may be mediated by increased RAGE signaling in the fetal brain.