R
R. Arthur Bouwman
Researcher at Eindhoven University of Technology
Publications - 73
Citations - 839
R. Arthur Bouwman is an academic researcher from Eindhoven University of Technology. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 14, co-authored 40 publications receiving 670 citations. Previous affiliations of R. Arthur Bouwman include VU University Medical Center.
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Journal ArticleDOI
SIH—a novel lipophilic iron chelator—protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death
Tomáš Šimůnek,Christa Boer,R. Arthur Bouwman,Ronald Vlasblom,Amanda M. G. Versteilen,Martin Štěrba,Vladimír Geršl,Radomír Hrdina,Přemysl Poňka,Jaap J. de Lange,Walter Paulus,René J. P. Musters +11 more
TL;DR: Iron chelation is presented as a very powerful tool by which oxidative stress-induced myocardial damage can be prevented.
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Reactive Oxygen Species–Induced Stimulation of 5′AMP-Activated Protein Kinase Mediates Sevoflurane-Induced Cardioprotection
Regis R. Lamberts,Geert Onderwater,Nazha Hamdani,M. Jumoke A. Vreden,Jeroen Steenhuisen,Etto C. Eringa,Stephan A. Loer,Ger J.M. Stienen,R. Arthur Bouwman +8 more
TL;DR: Sevoflurane-induced AMPK activation protects the heart against ischemia and reperfusion injury and relies on upstream production of ROS.
Journal ArticleDOI
Reactive Oxygen Species Precede Protein Kinase C-δ Activation Independent of Adenosine Triphosphate–sensitive Mitochondrial Channel Opening in Sevoflurane-induced Cardioprotection
R. Arthur Bouwman,René J. P. Musters,T. Brechje J. Van Beek-Harmsen,Jaap J. de Lange,Christa Boer +4 more
TL;DR: In sevoflurane-induced cardioprotection, ROS release but not mito K+ATP channel opening precedes PKC-&dgr; activation, which might be involved in the recruitment of PKC; to the cell membrane.
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Comparison of noninvasive continuous arterial waveform analysis (Nexfin) with transthoracic Doppler echocardiography for monitoring of cardiac output.
TL;DR: In this paper, the authors compare the Nexfin cardiac output (CO) with the CO obtained from transthoracic Doppler echocardiography (TTE) during routine cardiac function screening.
Comparison of noninvasive continuous arterial waveform analysis (Nexfin) with transthoracic Doppler echocardiography for monitoring of
TL;DR: Considering limits of precision of CO measurements with Doppler echocardiography (± 30%), the agreement between noninvasive CO measurement with the Nexfin and TTE is reasonable.