R
R. Hesterberg
Researcher at University of Marburg
Publications - 16
Citations - 551
R. Hesterberg is an academic researcher from University of Marburg. The author has contributed to research in topics: Diamine oxidase & Diamine oxidase activity. The author has an hindex of 11, co-authored 16 publications receiving 539 citations. Previous affiliations of R. Hesterberg include Polish Academy of Sciences.
Papers
More filters
Journal ArticleDOI
Distribution and properties of human intestinal diamine oxidase and its relevance for the histamine catabolism
Tadeusz Biegański,J. Kusche,Wilfried Lorenz,R. Hesterberg,C. D. Stahlknecht,Klaus-Dieter Feussner +5 more
TL;DR: High activities of diamine oxidase were measured in the intestinal tract of human subjects and of several mammalian species, considered to play a protective role against histamine in diseases such as ischaemic bowel syndrome, mesenteric infarction and ulcerative colitis.
Journal ArticleDOI
Comparison of the 14-C-putrescine assay with the NADH test for the determination of diamine oxidase: description of a standard procedure with a high precision and an improved accuracy.
TL;DR: The isotope assay was the more sensitive and convenient test, but due to its absolute specificity the NADH test was useful as a reference method and for the investigation of the substrate specificity of the DAO in various tissues and body fluids.
Journal ArticleDOI
Inhibition of human and canine diamine oxidase by drugs used in an intensive care unit: relevance for clinical side effects?
TL;DR: The observation that within a given therapeutic group some members inhibit and others do not, could be useful in choosing a therapy concept which minimizes the risk of a more severe ‘histamine’ reaction in seriously ill patients.
Journal ArticleDOI
Intestinal diamine oxidase and histamine release in rabbit mesenteric ischemia.
J. Kusche,Wilfried Lorenz,C. D. Stahlknecht,Hans Richter,R. Hesterberg,A. Schmal,Evi Hinterlang,Doris Weber,C. Ohmann +8 more
TL;DR: There is strong evidence for the protective role of intestinal diamine oxidase in intestinal ischemia and a monoexponential dose-response relationship was found between the specific diamine oxidation inhibitor aminoguanidine and reduced survival time.
Journal ArticleDOI
Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: fact or fictions?
TL;DR: Since the methods for histamine determination and those for measuring enzymic activities were not different in this study and in previous communications of the group the authors are convinced that the optimized tissue-sampling and-preparation techniques were responsible for the higher values in this communication.