R. L. Huguenin

TL;DR: The final octapeptide, L-histidyl- L-phenylalanyl-L-arginyl- l-tryptophanyl-glycyl-ϵ-CBO-L/L-lysyl-l-prolyl-V-valylamide is shown to be optically pure by leucine-aminopeptidase digestion.

TL;DR: After removal of the protective groups and purification by gel-filtration the free peptide obtained exhibited the physical, chemical and biological properties of the natural hormone.

TL;DR: In this paper, the syntheses of the alkaloids of the ergotoxine-group i.e. ergocristine, α- and β-ergokryptine, and ergocornine, are described.

TL;DR: Five peptides prepared by condensation of a tripeptide azide or a propionyl-dipeptides azide with a hexapeptide amide were found to be devoid of any biological activity and did not inhibit the corresponding natural hormones.

TL;DR: Six new analogues of Lysine-vasopressin have been synthesized by the 3 + 6 scheme and the analogues substituted in position 4 were found to still possess a significant level of activity, whereas those substituted in positions 5 or 7 were almost inactive.