R. Sawaya

TL;DR: Results show that the molecular approach to tumor classification can generate clinically meaningful patient stratification, and, more importantly, is an efficient class‐discovery tool for human gliomas, permitting the identification of previously unrecognized, clinically relevant tumor subsets.

TL;DR: It is concluded that GFAP- expressing astrocytes, with appropriate signaling abnormalities, can serve as the cell of origin for oligodendrogliomas,Astrocytomas, or mixed gliomas, and transferred MTA expression specifically to GFAP(+) cells in vivo using somatic cell gene transfer is achieved.

TL;DR: Investigation of cervical spinal cord irradiation in 90 rats showed that plasminogen activator inhibitor (PAI-1) was highly concentrated within and immediately adjacent to zones of necrosis at 145 days and was absent in normal tissue.

TL;DR: Enzymatic levels quantified by densitometry showed a twofold elevation in the levels of tPA and more than a tenfold increase in uPA after 120 days' irradiation; activity of uPA was increased threefold by day 2 and increased steadily with time compared to nonirradiated control samples.