R. Skowronski

TL;DR: The postprandial RP concentration in the Sf 20-400 lipoprotein fraction was higher than normal in patients with NIDDM, and associations have been defined in patients without diabetes mellitus between postPRandial insulin response, fasting TG and high density lipop Protein-cholesterol concentrations, and magnitude of postpr andial increase in TG-rich lipoproteins of intestinal origin.

TL;DR: The addition of metformin to sulfonylurea-treated patients with NIDDM not in good glycemic control significantly lowered fasting and postprandial plasma glucose concentrations, presumably due to the combination of enhanced glucose uptake and decreased hepatic glucose production.

TL;DR: Replacing saturated fat with CHO accentuates the magnitude of postprandial lipemia, and since TG-rich lipoproteins may be atherogenic, appropriate dietary advice for patients with type 2 diabetes may deserve reappraisal.

TL;DR: It is suggested that both plasma glycerol and NEFA concentrations are higher than normal in patients with Type 2 diabetes when measured at the same insulin concentration, both under basal conditions and in response to physiological hyperinsulinaemia.

TL;DR: The data indicate that the acute ingestion of high CHO (60%), low fat (25%) diets by patients with noninsulin-dependent diabetes mellitus led to little or no decrease in postprandial plasma or lipoprotein TG or cholesterol concentrations and an actual increase in concentration of potentially atherogenic small chylomicron and/or chylomaticron remnants.