R. Theiler

TL;DR: A single intervention with vitamin D plus calcium over a 3‐month period reduced the risk of falling by 49% compared with calcium alone, andMusculoskeletal function improved significantly in the Cal+D‐group (p = 0.0094).

TL;DR: Strong intranuclear immunostaining of the vitamin D receptor was detected in human muscle cells, the first in situ detection of the receptor in human skeletal muscle, and further research is needed in order to evaluate whether vitamin D3 receptor expression in human skeletons is age-dependent and varies between different muscles.

TL;DR: The discriminatory potential to classify subjects with or without vertebral fractures was tested cross‐sectionally with different methods for the measurement of bone status in a population‐based sample of postmenopausal women and the performance of QUS measurements is at least comparable with DXA measurements in identifying subjects with multiple vertebral fracture randomly selected from the population.

TL;DR: The association between nonvertebral fracture was higher for heel than phalangeal QUS, and the association between heel and phalanges was higher than other bone ultrasound measures.

TL;DR: The hypothesis that immobility, even in the presence of vitamin D deficiency, acts as an overriding influence on bone metabolism by promoting bone resorption (measured as urinary DPD) and increasing serum calcium independent of iPTH is supported.