R
Rafael Alfonso-Cristancho
Researcher at GlaxoSmithKline
Publications - 87
Citations - 23192
Rafael Alfonso-Cristancho is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 25, co-authored 54 publications receiving 19735 citations. Previous affiliations of Rafael Alfonso-Cristancho include University of Washington.
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Journal ArticleDOI
Preparing Electronic Clinical Data for Quality Improvement and Comparative Effectiveness Research: The SCOAP CERTAIN Automation and Validation Project
Emily Beth Devine,Daniel Capurro,Erik van Eaton,Rafael Alfonso-Cristancho,Allison Devlin,N. David Yanez,Meliha Yetisgen-Yildiz,David R. Flum,Peter Tarczy-Hornoch +8 more
TL;DR: In semi-automating data abstraction and conducting a rigorous validation, CERTAIN investigators will semi-Automate data collection to conduct QI and CER, while advancing the Learning Healthcare System.
Journal ArticleDOI
Effectiveness of a Medical vs Revascularization Intervention for Intermittent Leg Claudication Based on Patient-Reported Outcomes
Emily Beth Devine,Rafael Alfonso-Cristancho,N. David Yanez,Todd C. Edwards,Donald L. Patrick,Cheryl A. Armstrong,Allison Devlin,Rebecca Gaston Symons,Mark H. Meissner,Ellen L T Derrick,Danielle C. Lavallee,Larry Kessler,David R. Flum +12 more
TL;DR: Among patients with IC, those in the revascularization cohort had significantly improved function (Walking Impairment Questionnaire) and better health-related quality of life (VascuQol and EQ-5D), and fewer symptoms (CSI) at 12 months.
Journal ArticleDOI
BMI Trajectories Among the Severely Obese: Results From an Electronic Medical Record Population
Edwin S. Wong,Bruce C. M. Wang,Rafael Alfonso-Cristancho,David R. Flum,Sean D. Sullivan,Louis P. Garrison,David Arterburn +6 more
TL;DR: It is concluded that BMI changes over 5 years among individuals classified as severely obese are generally small and consistent with studies documenting BMI changes for individuals in other lower BMI categories.
Journal ArticleDOI
Series: Pragmatic trials and real world evidence: Paper 7. Safety, quality and monitoring.
Elaine A. Irving,Rutger van den Bor,Paco M J Welsing,Veronica Walsh,Rafael Alfonso-Cristancho,Catherine Harvey,Nadia Garman,Diederick E. Grobbee +7 more
TL;DR: This paper proposes a risk-based approach to the collection of non-drug-related non-serious adverse events and even serious events not related to treatment based on the risk profile of the medicine/class in the patient population of interest.
BMI trajectories Among the Severely Obese: Results From an Electronic Medical Record
PopulationS . Wong,Rafael Alfonso-Cristancho,David R. Flum,Sean D. Sullivan,Louis P. Garrison,David Arterburn +5 more
TL;DR: For example, Heo et al. as mentioned in this paper examined trajectories of BMI and weight change over time in the U.S. with an initial BMI of 35 or greater and found that a minimum threshold of 35 in conjunction with one or more severe comorbidities is required for bariatric surgery.