Showing papers by "Rafael Guerra Lund published in 2012"
TL;DR: It is concluded that a high proportion of users and professionals made use of medicinal plants, and of the large number of plants mentioned in the questionnaire, mauve was the most commonly used, mainly for the treatment of toothaches.
53 citations
TL;DR: The results indicate that the flower hexane extract obtained from M. spicata associated with M. rotundifolia presents an antineoplastic activity against KB and MCF-7, although an antiproliferative effect at a high concentration of the extract was observed toward NIH 3T3.
Abstract: This study assessed the antiproliferative effect in vitro of the flower hexane extract obtained from Mentha spicata associated with Mentha rotundifolia against the human breast adenocarcinoma (MCF-7), human mouth epidermal carcinoma (KB), and mouse embryonic fibroblast (NIH 3T3) cell lines, using sulforhodamine B (SRB) assay. A cell density of 2×104/well was seeded in 96-well plates, and samples at different concentrations ranging from 10 to 500 mg/mL were tested. The optical density was determined in an ELISA multiplate reader (Thermo Plate TP-Reader). Results demonstrated that the hexane extract presented antiproliferative activity against both the tumor cell lines KB and MCF-7, presenting a GI50 (MCF-7=13.09 mg/mL), TGI (KB=37.76 mg/mL), and IL50 (KB=291.07 mg/mL). Also, the hexane extract presented antiproliferative activity toward NIH 3T3 cells GI50 (183.65 mg/mL), TGI (280.54 mg/mL), and IL50 (384.59 mg/mL). The results indicate that the flower hexane extract obtained from M. spicata associ...
15 citations
TL;DR: Results suggest that M. arvensis hydroalcoholic extract may be considered a potentially antifungal agent against C. albicans, and a possible item for human antibiotic therapy, however, further biological tests on the plant's efficacy and side-effects are necessary before its use on humans.
Abstract: In vitro tests could be a valuable tool for the evaluation of medicinal plants' antimicrobial activity. Mentha arvensis of the Lamiaceae family is one of the most frequently traditional plants used in Brazil. Hydroalcoholic extracts of M. arvensis were analyzed for antimicrobial activity on Streptococcus mutans, Streptococcus sobrinus and Candida albicans. Three different assays (agar diffusion, broth macro- and micro- dilution methods) were used to evaluate antimicrobial activity. Although hydroalcoholic extracts of M. arvensis did not show any antibacterial effect, its antifungal activity against C. albicans was revealed. According to the micro-dilution broth assay, MIC of the hydroalcoholic extract from leaves of M. arvensis on Candida albicans strains ranged between 625 and 2500 μg mL -1 . Results suggest that M. arvensis hydroalcoholic extract may be considered a potentially antifungal agent against C. albicans, and a possible item for human antibiotic therapy. However, further biological tests on the plant's efficacy and side-effects are necessary before its use on humans.
3 citations
TL;DR: An understanding of HBU users’ characteristics and their associated social and demographic context may contribute towards a better reception and may confirm the UHS contribution towards universality and equality of public health care.
Abstract: Aim: The use of health services is a complex behavior and results from a series of determinants that includes the users’ social and demographic characteristics. The current survey interprets the social and demographic profile of Unified Health System (UHS; SUS in Portuguese) users from Pelotas RS Brazil, which was conducted by interviews with 333 users from five Health Basic Units (HBUs). Methods: The social and demographic characterization was deployed by the variables sex, age, occupation, city/town or district of origin, number of family members, use of continuous medication, diseases and family income. Results: HBU users were mostly women (82.4%), within the 30-40-year-old age range (21.4%), housewives (36.3%) from Pelotas (96.2%) and from the district of Fragata (26.1%). Families of users comprise mostly two to four members (66.6%), with an income of one to two minimum wages (66.2%). Fifty-one percent of the interviewees do not use continuous medication, while hypertension was the most cited disease (51.8%). Conclusions: An understanding of HBU users’ characteristics and their associated social and demographic context may contribute towards a better reception and may confirm the UHS contribution towards universality and equality of public health care.
2 citations
01 Dec 2012
TL;DR: In this article, the authors discuss the conhecimento dos mesmos acerca de sustentabilidade, separacao dos componentes solidos, tratamento das solucoes processadoras no consultorio, destino final dos residuos and uso correto do gerenciamento como ferramenta de marketing.
Abstract: Objetivo: Avaliar a segregacao, tratamento e destino dos residuos radiologicos dado pelos cirurgioesdentistas de Pelotas que possuem aparelhos de raios-X em uso no consultorio odontologico e cadastrados na Vigilância Sanitaria; e analisar o conhecimento dos mesmos acerca de sustentabilidade. Materiais e Metodos: Quarenta cirurgioes-dentistas de Pelotas-RS responderam um formulario contendo 16 perguntas que abordaram o conhecimento destes profissionais sobre a sustentabilidade, separacao dos componentes solidos do filme radiografico, tratamento das solucoes processadoras no consultorio, destino final dos residuos e uso correto do gerenciamento como ferramenta de marketing. Resultados: Verificou-se que 35,0% da amostra relatou lancar o revelador e o fixador em esgoto comum sem antes neutraliza-los. A maioria dos participantes (67,5%) afirmou acreditar no potencial poluidor da agua de lavagem do filme durante o seu processamento, embora 65,0% deles relataram descartar o material diretamente em esgoto comum. Com relacao a segregacao dos residuos solidos, 37,5% dos dentistas disseram nao separar os componentes do filme radiografico. A maior parte deles (90,0%) afirmou ter conhecimento sobre desenvolvimento sustentavel, 95,0% tentavam preservar o meio ambiente quando descartavam os residuos do seu consultorio e 70,0% acreditavam que a destinacao apropriada dos residuos poderia se mostrar economicamente viavel. Conclusoes: A maioria dos profissionais afirmou ter conhecimento de desenvolvimento sustentavel e tentar preservar o meio ambiente quando descartavam os residuos produzidos no consultorio. Ha dificuldade, por parte dos cirurgioes-dentistas, no descarte dos efluentes liquidos, mas grande parte consegue classificar e segregar adequadamente os residuos do filme radiografico. Descritores: Residuos odontologicos. Residuos toxicos. Desenvolvimento sustentavel. Radiografia.
1 citations