Higher cortical functions in man

1980 Preface * 1999 Preface * 1999 Acknowledgements * Introduction * 1 Circular Logic * 2 Phase Singularities (Screwy Results of Circular Logic) * 3 The Rules of the Ring * 4 Ring Populations * 5 Getting Off the Ring * 6 Attracting Cycles and Isochrons * 7 Measuring the Trajectories of a Circadian Clock * 8 Populations of Attractor Cycle Oscillators * 9 Excitable Kinetics and Excitable Media * 10 The Varieties of Phaseless Experience: In Which the Geometrical Orderliness of Rhythmic Organization Breaks Down in Diverse Ways * 11 The Firefly Machine 12 Energy Metabolism in Cells * 13 The Malonic Acid Reagent ('Sodium Geometrate') * 14 Electrical Rhythmicity and Excitability in Cell Membranes * 15 The Aggregation of Slime Mold Amoebae * 16 Numerical Organizing Centers * 17 Electrical Singular Filaments in the Heart Wall * 18 Pattern Formation in the Fungi * 19 Circadian Rhythms in General * 20 The Circadian Clocks of Insect Eclosion * 21 The Flower of Kalanchoe * 22 The Cell Mitotic Cycle * 23 The Female Cycle * References * Index of Names * Index of Subjects

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The geometry of biological time , by A. T. Winfree. Pp 544. DM68. Corrected Second Printing 1990. ISBN 3-540-52528-9 (Springer)

A number of closed-loop postulations to explain motor skills learning and performance phenomena have appeared recently, but each of these views suffers from either (a) logical problems in explaining the phenomena or (b) predictions that are not supported by the empirical evidence. After these difficulties are discussed, a new theory for discrete motor learning is proposed that seems capable of explaining the existing findings. The theory is based on the notion of the schema and uses a recall memory to produce movement and a recognition memory to evaluate response correctness. Some of the predictions are mentioned, research techniques and paradigms that can be used to test the predictions are listed, and data in support of the theory are presented.

A schema theory of discrete motor skill learning.

THE DISCHARGES carried in the optic nerve fibers contain all the information which the central nervous system receives from the retina. A correct interpretation of discharge patterns therefore constitutes an important step in the analysis of visual events. Further, investigations of nervous activity arising in the eye reveal many aspects of the functional organization of the neural elements within the retina itself. Following studies of discharges in the optic nerve of the eel’s eye by Adrian and Matthews (2,3), Hartline and his colleagues described the discharge pattern in the eye of the Limulus in a series of important and lucid papers (for a summary see 20). In the Limulus the relationship between the stimulus to the primary receptor cell and the nerve discharges proved relatively simple, apparently because the connection between sense cell and nerve fiber was a direct one. Thus, when stimulation is confined to one receptor the discharge in a single Limulus nerve fiber will provide a good indication of excitatory events which take place as a result of photochemical processes. Discharges last for the duration of illumination and their frequency is a measure of stimulus strength. Lately, however, it was shown by Hartline et al. (22) that inhibitory interactions may be revealed when several receptors are excited. On the whole, the Limulus preparation shows many features which are similar to other simple sense organs, for instance, stretch receptors. In the latter, however, instead of photochemical events, stretch-deformation acts as the adequate stimulus on sensory terminals and is translated into a characteristic discharge pattern. The discharge from the cold-blooded vertebrate retina (mainly frogs) proved much more complex. Hartline found three main types when recording from single optic nerve fibers: (i) “on” discharges, similar to those in the Limulus, firing for the duration of the light stimulus, (ii) “off” discharges appearing when a light stimulus was withdrawn, and (iii) ‘con-off” discharges, a combination of the former two, with activity confined mainly to onset and cessation of illumination. The mammalian discharge patterns were studied in a number of species by Granit and his co-workers in the course of their extensive work on the physiology of the visual system (summaries in 13, 15). On the whole, they did not observe any fundamental differences between frog and mammalian discharge types (see later).

Discharge patterns and functional organization of mammalian retina

An apparatus for cleaning and sterilizing objects, such as pharmaceutical caps, plugs and the like includes an autoclave chamber and a cleaning device having a cleaning drum mounted for a free rotation on a frame. The frame runs on rollers and can be moved in and out of the autoclave chamber. The cleaning drum has a hollow shaft provided within the drum with spray nozzles and mounted axially in line with a hollow drive shaft passing through one sidewall of the autoclave chamber free to turn and sealed. The drum shaft and the drive shaft may be coupled together by a coupling device. The frame may be released from the drum introduced into the autoclave chamber so that it is not located during the cleaning process in the autoclave chamber and thus will not constitute an additional source of contamination.

Ragnar Granit

Papers

Receptors and sensory perception

The basis of motor control

Influence of Stimulation of Central Nervous Structures on Muscle Spindles in Cat1

Centrifugal and antidromic effects on ganglion cells of retina.

Differentiation of tonic from phasic alpha ventral horn cells by stretch, pinna and crossed extensor reflexes.