R
Randall S. Hughes
Researcher at University of Texas Southwestern Medical Center
Publications - 35
Citations - 1473
Randall S. Hughes is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Radiation therapy & Head and neck cancer. The author has an hindex of 11, co-authored 32 publications receiving 1067 citations.
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Journal ArticleDOI
Consolidative Radiotherapy for Limited Metastatic Non-Small-Cell Lung Cancer: A Phase 2 Randomized Clinical Trial.
Puneeth Iyengar,Zabi Wardak,David E. Gerber,Vasu Tumati,Chul Ahn,Randall S. Hughes,Jonathan E. Dowell,Naga Cheedella,Lucien A. Nedzi,Kenneth D. Westover,Suprabha Pulipparacharuvil,Hak Choy,Robert Timmerman +12 more
TL;DR: Consolidative SAbR prior to maintenance chemotherapy appeared beneficial, nearly tripling PFS in patients with limited metastatic NSCLC compared with maintenance chemotherapy alone, with no difference in toxic effects.
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Phase II Trial of Stereotactic Body Radiation Therapy Combined With Erlotinib for Patients With Limited but Progressive Metastatic Non–Small-Cell Lung Cancer
Puneeth Iyengar,Brian D. Kavanagh,Zabi Wardak,I. Smith,Chul Ahn,David E. Gerber,Jonathan E. Dowell,Randall S. Hughes,Ramzi Abdulrahman,D. Ross Camidge,Laurie E. Gaspar,Robert C. Doebele,Paul A. Bunn,Hak Choy,Robert Timmerman +14 more
TL;DR: Use of SBRT with erlotinib for unselected patients with stage IV NSCLC as a second- or subsequent line therapy resulted in dramatic changes in patterns of failure, was well tolerated, and resulted in high PFS and OS, substantially greater than historical values for patients who only received systemic agents.
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Head and neck oncology during the COVID-19 pandemic: Reconsidering traditional treatment paradigms in light of new surgical and other multilevel risks.
Andrew T. Day,David J. Sher,Rebecca Lee,John M. Truelson,Larry L. Myers,Baran D. Sumer,Lenka Stankova,Brittny N. Tillman,Randall S. Hughes,Saad A. Khan,Eli Gordin +10 more
TL;DR: Head and neck cancer patients are generally at high-risk for COVID-19 infection and severe adverse outcomes, and urgent guidance in the delivery of safe, quality head and neck oncologic care is needed.
Journal ArticleDOI
Primary colonic lymphoma.
N. Doolabh,Thomas Anthony,Clifford Simmang,S. Bieligk,Edward L. Lee,Philip J. Huber,Randall S. Hughes,Richard H. Turnage +7 more
TL;DR: The colon is a rare location for gastrointestinal non‐Hodgkin's lymphoma and risk factors, presentation, treatment, and prognosis for primary colonic lymphoma are identified through review of a large tertiary care hospital system experience.
Journal ArticleDOI
Malignant Infiltration of the Liver Presenting as Acute Liver Failure
Nicole E. Rich,Corron Sanders,Randall S. Hughes,Robert J. Fontana,R. Todd Stravitz,Oren K. Fix,Steven Han,Willscott E. Naugler,Atif Zaman,William M. Lee +9 more
TL;DR: A large, multicenter ALF registry was examined and found only 27 cases of ALF attributed to malignancy, with 90% of the patients with lymphoma or leukemia had no history of cancer, compared with 25% of patients with breast cancer.