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Rashmirekha Pati

Researcher at KIIT University

Publications -  9
Citations -  911

Rashmirekha Pati is an academic researcher from KIIT University. The author has contributed to research in topics: Antimycobacterial & Drug carrier. The author has an hindex of 8, co-authored 9 publications receiving 636 citations.

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Nanoparticle Vaccines Against Infectious Diseases

TL;DR: This review article focuses on the applications of nanocarrier-based vaccine formulations and the strategies used for the functionalization of nanoparticles to accomplish efficient delivery of vaccines in order to induce desired host immunity against infectious diseases.
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Topical application of zinc oxide nanoparticles reduces bacterial skin infection in mice and exhibits antibacterial activity by inducing oxidative stress response and cell membrane disintegration in macrophages.

TL;DR: This in-depth study demonstrates properties of ZnO nanoparticles in infection prevention and treatment in several skin infection models, dissecting the potential mechanisms of action of these nanoparticles and paving the way to human applications.
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Zinc-Oxide Nanoparticles Exhibit Genotoxic, Clastogenic, Cytotoxic and Actin Depolymerization Effects by Inducing Oxidative Stress Responses in Macrophages and Adult Mice

TL;DR: Detailed pathological insights of ZnO-NP that impair cellular functions will enable to arbitrate their biological applications and give detailed pathological insights into the genotoxic, clastogenic, and cytotoxic effects of the particles on macrophages and in adult mice.
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In Vitro Cytotoxic Effects of Gold Nanoparticles Coated with Functional Acyl Homoserine Lactone Lactonase Protein from Bacillus licheniformis and Their Antibiofilm Activity against Proteus Species

TL;DR: It is concluded that at a specific dose, AuNPs coated with AiiA can kill bacteria without harming the host cells, thus representing a potential template for the design of novel antibiofilm and antibacterial protein drugs to decrease bacterial colonization and to overcome the problem of drug resistance.