R
Ravindra S. Dhumal
Researcher at Bharati Vidyapeeth University
Publications - 23
Citations - 1094
Ravindra S. Dhumal is an academic researcher from Bharati Vidyapeeth University. The author has contributed to research in topics: Cocrystal & Spray drying. The author has an hindex of 14, co-authored 23 publications receiving 995 citations. Previous affiliations of Ravindra S. Dhumal include University of Bradford.
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Cocrystalization and Simultaneous Agglomeration Using Hot Melt Extrusion
TL;DR: A single-step, scalable, solvent-free, continuous cocrystallization and agglomeration technology was developed using HME, offering flexibility for tailoring the cocrystal purity.
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Preparation of amorphous cefuroxime axetil nanoparticles by sonoprecipitation for enhancement of bioavailability.
Ravindra S. Dhumal,Shailesh V. Biradar,Shigeo Yamamura,Anant Paradkar,Anant Paradkar,Peter York +5 more
TL;DR: Sonoprecipitated CA nanoparticles showed enhanced dissolution rate and oral bioavailability in Wistar rat due to an increased solubility attributed to combination of effects like amorphization and nanonization with increased surface area and reduced diffusion pathway.
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Particle engineering using sonocrystallization: salbutamol sulphate for pulmonary delivery.
TL;DR: Application of ultrasound during anti-solvent crystallization resulted in fine elongated crystals (sonocrystallized SS; SCSS) compared to aggregates of large irregular crystals obtained without sonication, which favored formation of smaller crystals with narrow particle size distribution (PSD).
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Ultrasound assisted engineering of lactose crystals.
TL;DR: Ultrasound assisted in-situ seeding, followed by ordered growth in glycerin offers rapid technique for separation of nuclei induction from crystal growth yielding desirable characteristics for better dispersion and in-vitro deposition when employed as DPI carrier.
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Monitoring ibuprofen–nicotinamide cocrystal formation during solvent free continuous cocrystallization (SFCC) using near infrared spectroscopy as a PAT tool
TL;DR: It is suggested that NIR spectroscopy could be used to monitor cocrystal purity on an industrial scale using this continuous, solvent-free process.