R
Raymond P. Ward
Researcher at University of Washington
Publications - 6
Citations - 1155
Raymond P. Ward is an academic researcher from University of Washington. The author has contributed to research in topics: Serotonin & 5-HT receptor. The author has an hindex of 5, co-authored 6 publications receiving 1137 citations.
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Journal Article
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
TL;DR: The distinct structural and pharmacological properties of this receptor site indicate that it represents a completely novel subtype of serotonin receptor, and it is likely that this receptor may play a role in several neuropsychiatric disorders that involve serotonergic systems.
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Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry.
Raymond P. Ward,M.W. Hamblin,Jean E. Lachowicz,Beth J. Hoffman,David R. Sibley,Daniel M. Dorsa +5 more
TL;DR: The serotonin receptor subtype 6, which raises intracellular cyclic AMP via stimulatory G-proteins, has recently been cloned and characterized and the possibility is raised that this receptor may play an important role in mediating the effects of the atypical antipsychotic agents.
Journal ArticleDOI
Colocalization of serotonin receptor subtypes 5-ht2a, 5-ht2c, and 5-ht6 with neuropeptides in rat striatum
Raymond P. Ward,Daniel M. Dorsa +1 more
TL;DR: Several serotonin receptors are also prominently expressed in the striatum, but little is known about how they fit into the molecular neuroanatomy described above.
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Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-HT4 or 5-HT6 receptors following antipsychotic administration
Raymond P. Ward,Daniel M. Dorsa +1 more
TL;DR: It is concluded that the striatal Gs-coupled adenosine A2a receptor is an important mediator of the molecular and behavioral sequelae following haloperidol administration.
Journal Article
Role of adenosine and N-methyl-D-aspartate receptors in mediating haloperidol-induced gene expression and catalepsy.
TL;DR: Results indicate that the haloperidol-induced increases in c-fos and NT gene expression in the dorsolateral striatum and catalepsy are driven largely by adenosine and glutamatergic inputs acting at A(2A) and NMDA receptors.