R
Reagan McRae
Researcher at Georgia Institute of Technology
Publications - 8
Citations - 1211
Reagan McRae is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Microscopy & Live cell imaging. The author has an hindex of 8, co-authored 8 publications receiving 1128 citations.
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Journal ArticleDOI
In Situ Imaging of Metals in Cells and Tissues
TL;DR: The aim of this review is to provide an overview of the most recent achievements in trace metal imaging while at the same time also offering a historical perspective of this rapidly evolving research field.
Journal ArticleDOI
Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy
Liuchun Yang,Reagan McRae,Maged Henary,Raxit Patel,Barry Lai,Stefan Vogt,Christoph J. Fahrni +6 more
TL;DR: The presented data provide a coherent picture with strong evidence for a kinetically labile copper pool, which is predominantly localized in the mitochondria and the Golgi apparatus.
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Molecular recognition based on low-affinity polyvalent interactions: selective binding of a carboxylated polymer to fibronectin fibrils of live fibroblast cells.
TL;DR: The studies demonstrate that selective molecular recognition of biomolecules in the complex environment of the extracellular matrix can be achieved by means of nonspecific low-affinity polyvalent interactions.
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Correlative microXRF and optical immunofluorescence microscopy of adherent cells labeled with ultrasmall gold particles
TL;DR: MicroXRF proved to be sufficiently sensitive to image the location and structural details of the Au-labeled organelles, which correlated well with the subcellular distribution visualized by means of optical fluorescence microscopy.
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Subcellular redistribution and mitotic inheritance of transition metals in proliferating mouse fibroblast cells
TL;DR: Synchrotron X-ray fluorescence microscopy of non-synchronized NIH 3T3 fibroblasts revealed an intriguing redistribution dynamics that defines the inheritance of trace metals during mitosis, suggesting a prominent physiological role that lies beyond the requirement of Zn as a cofactor in metalloproteins or messenger in signaling pathways.