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Rein M G J Houben
Researcher at University of London
Publications - 124
Citations - 7734
Rein M G J Houben is an academic researcher from University of London. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 33, co-authored 98 publications receiving 5399 citations. Previous affiliations of Rein M G J Houben include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling.
Rein M G J Houben,Peter J. Dodd +1 more
TL;DR: Investment in new tools to improve diagnosis and treatment of those with LTBI at risk of progressing to disease is urgently needed to address this latent reservoir if the 2050 target of eliminating TB is to be reached.
Journal ArticleDOI
Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study.
Andrew Clark,Mark Jit,Charlotte Warren-Gash,Bruce Guthrie,Harry H.X. Wang,Stewart W Mercer,Colin Sanderson,Martin McKee,Christopher Troeger,Kanyin L Ong,Francesco Checchi,Pablo Perel,Sarah Joseph,Hamish Gibbs,Amitava Banerjee,Rosalind M Eggo,Emily Nightingale,Kathleen M. O’Reilly,Thibaut Jombart,W. John Edmunds,Alicia Rosello,Fiona Yueqian Sun,Katherine E. Atkins,Nikos I Bosse,Samuel Clifford,Timothy W Russell,Arminder K Deol,Yang Liu,Simon R Procter,Quentin J Leclerc,Graham F. Medley,Gwen Knight,James D Munday,Adam J. Kucharski,Carl A. B. Pearson,Petra Klepac,Kiesha Prem,Rein M G J Houben,Akira Endo,Stefan Flasche,Nicholas G Davies,Charlie Diamond,Kevin van Zandvoort,Sebastian Funk,Megan Auzenbergs,Eleanor M Rees,Damien C. Tully,Jon C Emery,Billy J Quilty,Sam Abbott,Ch. Julián Villabona-Arenas,Stéphane Hué,Joel Hellewell,Amy Gimma,Christopher I Jarvis +54 more
TL;DR: These estimates provide a starting point for considering the number of individuals that might need to be shielded or vaccinated as the global pandemic unfolds, and focus on underlying conditions rather than other risk factors such as ethnicity, socioeconomic deprivation, and obesity.
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Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study.
Nicholas G Davies,Adam J. Kucharski,Rosalind M Eggo,Amy Gimma,W. John Edmunds,Thibaut Jombart,Kathleen M. O’Reilly,Akira Endo,Joel Hellewell,Emily Nightingale,Billy J Quilty,Christopher I Jarvis,Timothy W Russell,Petra Klepac,Nikos I Bosse,Sebastian Funk,Sam Abbott,Graham F. Medley,Hamish Gibbs,Carl A. B. Pearson,Stefan Flasche,Mark Jit,Samuel Clifford,Kiesha Prem,Charlie Diamond,Jon C Emery,Arminder K Deol,Simon R Procter,Kevin van Zandvoort,Yueqian Fiona Sun,James D Munday,Alicia Rosello,Megan Auzenbergs,Gwen Knight,Rein M G J Houben,Yang Liu +35 more
TL;DR: In this article, the authors used a stochastic age-structured transmission model to explore a range of intervention scenarios, tracking 66·4 million people aggregated to 186 county-level administrative units in England, Wales, Scotland, and Northern Ireland.
Journal ArticleDOI
Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study.
Adam J. Kucharski,Petra Klepac,Petra Klepac,Andrew J. K. Conlan,Stephen M Kissler,Maria L Tang,Hannah Fry,Julia R. Gog,W. John Edmunds,Jon C Emery,Graham F. Medley,James D Munday,Timothy W Russell,Quentin J Leclerc,Charlie Diamond,Simon R Procter,Amy Gimma,Fiona Yueqian Sun,Hamish Gibbs,Alicia Rosello,Kevin van Zandvoort,Stéphane Hué,Sophie Meakin,Arminder K Deol,Gwen Knight,Thibaut Jombart,Anna M Foss,Nikos I Bosse,Katherine E. Atkins,Billy J Quilty,Rachel Lowe,Kiesha Prem,Stefan Flasche,Carl A. B. Pearson,Rein M G J Houben,Emily Nightingale,Akira Endo,Damien C. Tully,Yang Liu,Julian Villabona-Arenas,Kathleen M. O’Reilly,Sebastian Funk,Rosalind M Eggo,Mark Jit,Eleanor M Rees,Joel Hellewell,Samuel Clifford,Christopher I Jarvis,Sam Abbott,Megan Auzenbergs,Nicholas G Davies,David Simons +51 more
TL;DR: Self-isolation and contact tracing would be more likely to achieve control of severe acute respiratory syndrome coronavirus 2 transmission if combined with moderate physical distancing measures.
Journal ArticleDOI
Sex Differences in Tuberculosis Burden and Notifications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.
Katherine C. Horton,Peter MacPherson,Rein M G J Houben,Richard G. White,Elizabeth L. Corbett,Elizabeth L. Corbett +5 more
TL;DR: TB prevalence is significantly higher among men than women in low- and middle-income countries, with strong evidence that men are disadvantaged in seeking and/or accessing TB care in many settings.