Reine Bareille

TL;DR: This work demonstrates that a laser assisted cell printer can deposit cells with a microscale resolution, at a speed of 5 kHz and with computer assisted geometric control, and successfully implemented such a cell printing precision to print miniaturized tissue like layouts with de novo high cell density and micro scale organization.

TL;DR: Should these results be confirmed in humans, bone reconstruction could be carried out earlier than previously thought and in better conditions than expected, the membrane playing the role of an in situ delivery system for growth and osteoinductive factors.

TL;DR: Results of high-throughput laser printing of a biopolymer, biomaterials and human endothelial cells and nano-sized hydroxyapatite synthesized by wet precipitation are presented, demonstrating the interest in this technique for three-dimensional tissue construction.

TL;DR: Investigation of the interaction between human umbilical vein endothelial cells (HUVEC) and human bone marrow stromal cells (HBMSC) revealed that connexin43 (Cx43), a specific gap junction protein, is expressed not only in HBMSC but also in the endothelial cell network and that these two cell types can communicate via a gap junctional channel constituted at least by Cx43.

TL;DR: The results suggest that the intercommunication between endothelial cells and osteoblastic‐like cells requires not only diffusible factors, but also involving cell membrane proteins, which is an important mediator for the angiogenic process involved in bone physiology.