Remco H.S. Westerink

TL;DR: It is more than likely that in the following decade PC12 cells will continue to serve as a model to study exocytosis, which has some advantages over other models for neurosecretion, including chromaffin cells.

TL;DR: The increased hazard for developmental neurotoxicity by hydroxylated (OH-)PBDEs compared with their parent congeners via direct neurotoxicity and thyroid disruption clearly warrants further investigation into a) the role of oxidative metabolism in producing active metabolites of PBDEs and their impact on brain development; b) concentrations of parent and OH-PBDES in the brain; and c) interactions between different environmental contaminants during exposure to mixtures, which may increase neurotoxicity.

TL;DR: Outdoor air pollution has been linked to several health effects including oxidative stress and neuroinflammation that may ultimately result in neurodegeneration and cognitive impairment and this review aims to evaluate the relationship between exposure to inhaled ambient particles and neurodegenersation.

TL;DR: The combined data, although fragmentary, indicate that exposure to micro- and nanoplastics can induce oxidative stress, potentially resulting in cellular damage and an increased vulnerability to develop neuronal disorders.

TL;DR: The history of pesticide usage and the neurotoxicity of selected classes of pesticides, including insecticides, herbicides, and fungicides, to humans and experimental animals are reviewed and linkages between exposure to pesticides and risk of neurological disease and dysfunction in humans are linked.