F
Flemming R. Cassee
Researcher at Utrecht University
Publications - 285
Citations - 18894
Flemming R. Cassee is an academic researcher from Utrecht University. The author has contributed to research in topics: Inhalation exposure & Chemistry. The author has an hindex of 74, co-authored 259 publications receiving 16084 citations. Previous affiliations of Flemming R. Cassee include University of California, Los Angeles & National Oceanography Centre, Southampton.
Papers
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Journal ArticleDOI
Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5.
Nicole A.H. Janssen,Gerard Hoek,Milena Simic-Lawson,Paul Fischer,Leendert van Bree,Harry ten Brink,Menno Keuken,Richard Atkinson,H. Ross Anderson,Bert Brunekreef,Flemming R. Cassee +10 more
TL;DR: In this article, the authors compared the potential health benefits of a hypothetical traffic abatement measure, using near-roadway concentration increments of BCP and PM2.5 based on data from prior studies.
Journal ArticleDOI
Adverse cardiovascular effects of air pollution
Nicholas L. Mills,Ken Donaldson,Paddy W Hadoke,Nicholas A. Boon,William MacNee,Flemming R. Cassee,Thomas Sandström,Anders Blomberg,David E. Newby +8 more
TL;DR: An increased understanding of the mediators and mechanisms of these processes is necessary if the authors are to develop strategies to protect individuals at risk and reduce the effect of air pollution on cardiovascular disease.
Journal ArticleDOI
Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment
TL;DR: Overall assessment of the cancer risk of aldehydes in the diet leads to the conclusion that formaldehyde, acrolein, citral and vanillin are no dietary risk factors, and that the opposite may be true for acetaldehyde, crotonaldehyde and furfural.
Journal ArticleDOI
Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement.
Jon G Ayres,Paul J. A. Borm,Flemming R. Cassee,Vincent Castranova,Ken Donaldson,A.J. Ghio,Roy M. Harrison,Robert C. Hider,Frank J. Kelly,Ingeborg M. Kooter,Francelyne Marano,Robert L. Maynard,Ian Mudway,Andre E. Nel,Constantinos Sioutas,Steve Smith,Armelle Baeza-Squiban,Arthur K. Cho,Sean T Duggan,John R. Froines +19 more
TL;DR: In vitro test methods have an important role to play in the screening of toxicity in airborne particulate matter and nanoparticles and offer large cost advantages relative to human or animal inhalation studies and animal in vivo installation experiments.
Journal ArticleDOI
Inhaled Nanoparticles Accumulate at Sites of Vascular Disease
Mark R. Miller,Jennifer Raftis,Jeremy P. Langrish,Steven G. McLean,Pawitrabhorn Samutrtai,Shea P. Connell,Simon Wilson,Alex T. Vesey,Paul H. B. Fokkens,A. John F. Boere,Petra Krystek,Colin Campbell,Patrick W. F. Hadoke,Ken Donaldson,Flemming R. Cassee,David E. Newby,Rodger Duffin,Nicholas L. Mills +17 more
TL;DR: Translocation of inhaled nanoparticles into the systemic circulation and accumulation at sites of vascular inflammation provides a direct mechanism that can explain the link between environmental nanoparticles and cardiovascular disease and has major implications for risk management in the use of engineered nanomaterials.