Renate Solf

TL;DR: Cells grown in the alkaloid showed an increased capacity to bind Escherichia coli B886, a bacterium that binds to high mannose glycoproteins, and an increasing binding of [3H]concanavalin A.

TL;DR: Swainsonine is an indolizidine alkaloid that inhibits glycoprotein processing by inhibiting mannosidase II as discussed by the authors, and has been shown to be cytotoxic to mammalian cells.

TL;DR: Parallel investigations with rifampicin revealed partial cross-resistance, which was more marked in sorangicin A-resistant mutants than in rifampsicin- resistant mutants.

TL;DR: It was shown that although about 5% of ingested E. coli B-1385 remained viable for at least 3 h after being ingested by PMN, the surviving bacteria may have become damaged as shown by a decreased ability to incorporate [ 3 H]uracil into RNA when released from PMN.