Renee Gaspard

TL;DR: This work has optimized all aspects of the process, including PCR amplification of target cDNA clones, microarray printing, probe labeling and hybridization, and has developed strategies for data normalization and analysis.

TL;DR: A 19,200-element human cDNA microarray is used to profile transcription in three paired cell-line models of colorectal tumor metastasis and 176 genes are identified that appear to be differentially expressed in all highly metastatic cell lines relative to their reference.

TL;DR: This study provides the most comprehensive available survey of gene expression changes in response to acute and chronic ANG II treatment, verifying results from disparate studies, and suggests mechanisms that provide novel insight into the etiology of hypertensive heart disease and possible therapeutic interventions that may help to mitigate its effects.

TL;DR: The first genomewide characterization of the transcriptional changes within macrophages infected with B. anthracis and the identification of several hundred host genes that were differentially expressed during this intracellular stage of infection are reported.

TL;DR: In this article, a signaling cascade regulating cyclooxygenase-2 (COX-2), a pivotal pro-inflammatory enzyme expressed in rheumatic and osteoarthritic, but not normal, cartilage, was elucidated using microarray data coupled with bioinformatics tools.