R
Renganathan Arun
Researcher at Bharathidasan University
Publications - 12
Citations - 859
Renganathan Arun is an academic researcher from Bharathidasan University. The author has contributed to research in topics: Silver nanoparticle & Oxidative stress. The author has an hindex of 9, co-authored 12 publications receiving 739 citations.
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Journal ArticleDOI
Biogenic silver nanoparticles for cancer treatment: An experimental report
Murugaraj Jeyaraj,Gnanasekar Sathishkumar,Ganeshan Sivanandhan,Davoodbasha MubarakAli,Manoharan Rajesh,Renganathan Arun,Gnanajothi Kapildev,Markandan Manickavasagam,Nooruddin Thajuddin,Kumpati Premkumar,Andy Ganapathi +10 more
TL;DR: In this article, the authors investigated the in vitro cytotoxicity effect of biogenic silver nanoparticles (AgNPs) against human breast cancer (MCF-7) cells towards the development of anticancer agent.
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An investigation on the cytotoxicity and caspase-mediated apoptotic effect of biologically synthesized silver nanoparticles using Podophyllum hexandrum on human cervical carcinoma cells.
Murugaraj Jeyaraj,Manoharan Rajesh,Renganathan Arun,Davoodbasha MubarakAli,Gnanasekar Sathishkumar,Ganeshan Sivanandhan,Gnanajothi Kapil Dev,Markandan Manickavasagam,Kumpati Premkumar,Nooruddin Thajuddin,Andy Ganapathi +10 more
TL;DR: The overall result indicates that AgNPs can selectively inhibit the cellular mechanism of HeLa by DNA damage and caspase mediated cell death and gives an alternative avenue to treat human cancer effectively.
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An evidence on G2/M arrest, DNA damage and caspase mediated apoptotic effect of biosynthesized gold nanoparticles on human cervical carcinoma cells (HeLa)
Murugaraj Jeyaraj,Renganathan Arun,Gnanasekar Sathishkumar,Davoodbasha MubarakAli,Manoharan Rajesh,Ganeshan Sivanandhan,Gnanajothi Kapildev,Markandan Manickavasagam,Nooruddin Thajuddin,Andy Ganapathi +9 more
TL;DR: It was evidenced that AuNPs treated cells are undergone apoptosis through the activation of caspase cascade which subsequently leads to mitochondrial dysfunction which proves that biogenic colloidal AuNps can be developed as a promising drug candidature for human cervical cancer therapy.
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Role of Syzygium cumini seed extract in the chemoprevention of in vivo genomic damage and oxidative stress.
TL;DR: In this article, the role of Jamun seed extract (JSE) as a chemoprotective agent against in vivo oxidative stress and genomic damage was evaluated in mice which received JSE orally for 5 days before exposure to genotoxic carcinogens urethane (URE) and 7,12-dimethyl benz( a )anthracene (DMBA).
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Synthesis, nucleic acid binding, anticancer and antimicrobial activities of polymer–copper(II) complexes containing intercalative phenanthroline ligand(DPQ)
TL;DR: In this paper, the binding properties of polymer-copper(II) complexes with both CT-DNA and yeast tRNA were investigated using the disk diffusion method and the AO/EB staining.