R
Reza Wakili
Researcher at Montreal Heart Institute
Publications - 5
Citations - 834
Reza Wakili is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial tachycardia & Heart failure. The author has an hindex of 4, co-authored 5 publications receiving 737 citations. Previous affiliations of Reza Wakili include Université de Montréal.
Papers
More filters
Journal ArticleDOI
Recent advances in the molecular pathophysiology of atrial fibrillation
TL;DR: The ways in which cardiac disease states, extracardiac factors, and abnormal genetic control lead to the arrhythmia are discussed, including the potential therapeutic implications that might arise from an improved mechanistic understanding.
Journal ArticleDOI
MicroRNA29: A Mechanistic Contributor and Potential Biomarker in Atrial Fibrillation
Kristin Dawson,Reza Wakili,Balázs Ördög,Sebastian Clauss,Yu Chen,Yu-ki Iwasaki,Niels Voigt,Xiao Yan Qi,Moritz F. Sinner,Dobromir Dobrev,Stefan Kääb,Stanley Nattel +11 more
TL;DR: MiR29 likely plays a role in atrial fibrotic remodeling and may have value as a biomarker and/or therapeutic target and in a CHF-related AF animal model.
Journal ArticleDOI
Multiple Potential Molecular Contributors to Atrial Hypocontractility Caused by Atrial Tachycardia Remodeling in Dogs
Reza Wakili,Yung-Hsin Yeh,Xiao Yan Qi,Maura Greiser,Denis Chartier,Kunihiro Nishida,Ange Maguy,Louis-Robert Villeneuve,Peter Boknik,Niels Voigt,Judith Krysiak,Stefan Kääb,Ursula Ravens,Wolfgang A. Linke,Gerrit J.M. Stienen,Yanfen Shi,Jean-Claude Tardif,Ulrich Schotten,Dobromir Dobrev,Stanley Nattel +19 more
TL;DR: The complex mechanistic basis of the atrial hypocontractility associated with AF argues for upstream therapeutic targeting rather than interventions directed toward specific downstream pathophysiological derangements.
Journal ArticleDOI
Role of constitutively active acetylcholine-mediated potassium current in atrial contractile dysfunction caused by atrial tachycardia remodelling.
Sang-Ho Koo,Reza Wakili,Jung-Ho Heo,Denis Chartier,Hyun-Su Kim,Sun-Jung Kim,Jae Woo Lee,Xiao Yan Qi,Stanley Nattel,Tae-Joon Cha +9 more
TL;DR: Up-regulated I(KAChc) contributes to AF-related contractile dysfunction and could be a novel target to prevent hypocontractility-related thrombo-embolic complications.