Riccardo Spagna

TL;DR: SIR97 is the integration of two programs, SIR92 and CAOS, the first devoted to the solution of crystal structures by direct methods, the second to refinement via least-squares–Fourier procedures.

TL;DR: SIR2004 as mentioned in this paper is the evolution of the SIR2002 program, which is devoted to the solution of crystal structures by direct and Patterson methods, and it is able to solve ab initio both small/medium-size structures as well as macromolecules (up to 2000 atoms in the asymmetric unit).

TL;DR: Giacovazzo et al. as mentioned in this paper presented an overview of the work of the Dipartimento di Scienze della Terra Piazza UniversitaÁ, 06100 Perugia, Italy, Istituto di Cristallografia, CNR.

TL;DR: SIR88 as discussed by the authors is an integrated package of computer programs for the solution of crystal structures, based on the estimation of one-and two-phase structure seminvariants and three-and fourphase structure invariants according to the theory of representations.

TL;DR: Is a suite of computer programs devoted to protein crystal structure determination by X-ray crystallography, which automatically uses the above information to phase protein reflections, and may succeed even with structures with up to 6000 non-H atoms in the asymmetric unit.