From the Publisher: 
The accessible presentation of this book gives both a general view of the entire computer vision enterprise and also offers sufficient detail to be able to build useful applications. Users learn techniques that have proven to be useful by first-hand experience and a wide range of mathematical methods. A CD-ROM with every copy of the text contains source code for programming practice, color images, and illustrative movies. Comprehensive and up-to-date, this book includes essential topics that either reflect practical significance or are of theoretical importance. Topics are discussed in substantial and increasing depth. Application surveys describe numerous important application areas such as image based rendering and digital libraries. Many important algorithms broken down and illustrated in pseudo code. Appropriate for use by engineers as a comprehensive reference to the computer vision enterprise.

Computer vision : a modern approach = 计算机视觉 : 一种现代的方法

http://academic.oup.com/milmed/article-pdf/146/7/506/24126715/milmed-146-7-506.pdf

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Multicomponent reactions (MCRs) receive increasing attention because they address both diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively complex structures can be generated from simple starting materials in a single reaction step. The ever increasing need for optically pure compounds for pharmaceutical and agricultural applications as well as for catalysis promotes the development of asymmetric multicomponent reactions. In recent years, asymmetric multicomponent reactions have been applied to the total synthesis of various enantiopure natural products and commercial drugs, reducing the number of required reaction steps significantly. Although many developments in diastereoselective MCRs have been reported, the field of catalytic enantioselective MCRs has just started to blossom. This critical review describes developments in both diastereoselective and catalytic enantioselective multicomponent reactions since 2004. Significantly broadened scopes, new techniques, more environmentally benign methods and entirely novel MCRs reflect the increasingly inventive paths that synthetic chemist follow in this field. Until recently, enantioselective transition metal-catalyzed MCRs represented the majority of catalytic enantioselective MCRs. However, metal contamination is highly undesirable for drug synthesis. The emergence of organocatalysis greatly influences the quest for new asymmetric MCRs.

Recent developments in asymmetric multicomponent reactions.

Textbook of biochemistry with clinical correlations , 4th edn TM Devlin, ed pp xvii + 1186, illustrated Wiley-Liss, New York, 1997 £2995, hardback

This beautifully illustrated and well-written book, with an impressive array of authors, is aimed at both undergraduate and postgraduate level As the editor states in the preface, it is not intended to be a compendium of biochemistry but rather emphasises the biochemistry of mammalian cells The first 22 chapters cover …

Textbook of biochemistry with clinical correlations

Diketopiperazines : biological activity and synthesis

Different arabinosides and ribosides, viz. Ara‐DDA or 9(1‐β‐d‐arabinofuranosyl) 1,3‐dideazaadenine (6), Ara‐NDDP or 9(1‐β‐d‐arabinofuranosyl) 4‐nitro‐1,3‐dideazapurine (7), Ara‐DKP or 1(1‐β‐d‐arabinofuranosyl) diketopiperazine (8), Ribo‐DDA or 9(1‐β‐d‐ribofuranosyl) 1,3‐dideazaadenine (9) and Ribo‐NDDP or 9(1‐β‐d‐ribofuranosyl) 4‐nitro‐1,3‐dideazapurine (10) have been synthesized as probable antiviral agents. The arabinosides have been synthesized using the catalyst TDA‐1 that causes stereospecific formation of β‐nucleosides while a one‐pot synthesis procedure was adopted for the synthesis of the ribonucleosides where β‐anomers were obtained in higher yields. All the five nucleoside analogs have been screened for antiviral property against HIV‐1 (IIIB), HSV‐1 and 2, parainfluenza‐3, reovirus‐1 and many others. It was observed that arabinosides had greater inhibitory action than ribosides. The compound 7 or Ara‐NDDP has shown maximum inhibition of HIV‐1 replication than the rest of the molecules with an IC...

Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine.

Various multimodal medical images like computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography, single photon emission CT and structural MRI have different characteristics and carry different types of complementary anatomical and functional information. Therefore, fusion of multimodal images is required, in order to achieve good spatial resolution images carrying both anatomical and functional information. In this work, the authors have proposed a fusion technique based on curvelet transform. Curvelet transform is a multiscale, multidirectional transform having anisotropic property and is very efficient in capturing edge points in images. Edges in an image are the important information carrying points used to show better visual structure of the image. They use local energy-based fusion rule which is more effective than single pixel-based fusion rules. Comparison of the proposed method with other existing spatial and wavelet transform based methods, in terms of visual and quantitative measures show the effectiveness of the proposed method. For quantitative analysis of the method, they used five fusion metrics as entropy, standard deviation, edge-strength, sharpness and average gradient.

https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/iet-cvi.2015.0251

Local energy-based multimodal medical image fusion in curvelet domain

Multimodal Medical Image Fusion in Dual Tree Complex Wavelet Transform Domain Using Maximum and Average Fusion Rules

The objective of image fusion is to combine relevant information from two or more images of the same scene into a single composite image which is more informative and is more suitable for human and machine perception. In recent past, different methods of image fusion have been proposed in literature both in spatial domain and wavelet domain. Spatial domain based methods produce spatial distortions in the fused image. Spatial domain distortion can be well handled by the use of wavelet transform based image fusion methods. In this paper, we propose a pixel-level image fusion scheme using multiresolution Biorthogonal wavelet transform (BWT). Wavelet coefficients at different decomposition levels are fused using absolute maximum fusion rule. Two important properties wavelet symmetry and linear phase of BWT have been exploited for image fusion because they are capable to preserve edge information and hence reducing the distortions in the fused image. The performance of the proposed method have been extensively tested on several pairs of multifocus and multimodal images both free from any noise and in presence of additive white Gaussian noise and compared visually and quantitatively against existing spatial domain methods. Experimental results show that the proposed method improves fusion quality by reducing loss of significant information available in individual images. Fusion factor, entropy and standard deviation are used as quantitative quality measures of the fused image.

Biorthogonal wavelet transform based image fusion using absolute maximum fusion rule

Background: Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis. Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed precursor, needed for fatty acid synthesis. Biotin carboxyl carrier protein (BCCP) provides the co-factor for catalytic activity of ACC. Methodology/Principal Findings: BPL/BirA (Biotin Protein Ligase), and its substrate, biotin carboxyl carrier protein (BCCP) of Mycobacterium tuberculosis (Mt) were cloned and expressed in E. coli BL21. In contrast to EcBirA and PhBPL, the similar to 29.5 kDa MtBPL exists as a monomer in native, biotin and bio-5'AMP liganded forms. This was confirmed by molecular weigt profiling by gel filtration on Superdex S-200 and Dynamic Light Scattering (DLS). Computational docking of biotin and bio-5'AMP to MtBPL show that adenylation alters the contact residues for biotin. MtBPL forms 11 H-bonds with biotin, relative to 35 with bio-5'AMP. Docking simulations also suggest that bio-5'AMP hydrogen bonds to the conserved `GRGRRG' sequence but not biotin. The enzyme catalyzed transfer of biotin to BCCP was confirmed by incorporation of radioactive biotin and by Avidin blot. The K-m for BCCP was similar to 5.2 mu M and similar to 420 nM for biotin. MtBPL has low affinity (K-b = 1.06 x 10(-6) M) for biotin relative to EcBirA but their K-m are almost comparable suggesting that while the major function of MtBPL is biotinylation of BCCP, tight binding of biotin/bio-5'AMP by EcBirA is channeled for its repressor activity. Conclusions/Significance: These studies thus open up avenues for understanding the unique features of MtBPL and the role it plays in biotin utilization in M. tuberculosis.

/pdf/ligand-specificity-of-group-i-biotin-protein-ligase-of-17pxpf7aam.pdf

Richa Srivastava

Papers

Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine.

Local energy-based multimodal medical image fusion in curvelet domain

Multimodal Medical Image Fusion in Dual Tree Complex Wavelet Transform Domain Using Maximum and Average Fusion Rules

Biorthogonal wavelet transform based image fusion using absolute maximum fusion rule

Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis.