R
Richard A. Couch
Researcher at Shire plc
Publications - 18
Citations - 1161
Richard A. Couch is an academic researcher from Shire plc. The author has contributed to research in topics: Drug delivery & Dosage form. The author has an hindex of 12, co-authored 18 publications receiving 1156 citations.
Papers
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Journal Article
Fast-dissolving tablets
TL;DR: This artide describes existing fast-dissolving technologies and discusses several techniques used to formulate such tablets, namely tablet molding, freeze-drying, spray-Drying, sublimation, disintegrant addition, and the use of sugar-based excipients.
Patent
Oral pulsed dose drug delivery system
Beth A. Burnside,Xiaodi Guo,Kimberley Fiske,Richard A. Couch,Donald J. Treacy,Rong-Kun Chang,Charlotte M Mcguinness,Edward M. Rudnic +7 more
TL;DR: In this paper, a multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate release component and an enteric delayed-release component, is presented.
Patent
Drug formulations having reduced abuse potential
TL;DR: In this article, a drug formulation having reduced abuse potential which contains one or more of (1) a bittering agent, (2) a bright deterrent/indicator dye and (3) fine insoluble particulate matter.
Journal Article
Systemic drug delivery via the buccal mucosal route
TL;DR: The structure and environment of the oral mucosa is discussed, highlighting the experimental methods used in the assessment of buccal drug permeation and absorption, and the current status ofbuccal permeation enhancers as well as buCCal drug delivery systems are assessed.
Patent
Osmotic drug delivery system
Edward M. Rudnic,Beth A. Burnside,Henry H. Flanner,Sandra E. Wassink,Richard A. Couch,Jill E. Pinkett +5 more
TL;DR: An osmotic drug delivery system, preferably in tablet form, which dispenses a therapeutic agent having limited water solubility in solubilized form, is described in this paper.