R
Richard A Padgett
Researcher at Salk Institute for Biological Studies
Publications - 1
Citations - 89
Richard A Padgett is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Chromosome 7 (human) & Chromosome 21. The author has an hindex of 1, co-authored 1 publications receiving 88 citations.
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Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.
TL;DR: Syrian hamster cells resistant to N-(phosphonacetyl)-L-aspartate (PALA), a specific inhibitor of the aspartate transcarbamylase activity of the multifunctional protein CAD, overproduce this protein as a result of amplification of the CAD gene.