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Richard B. van Breemen

Researcher at Oregon State University

Publications -  370
Citations -  16117

Richard B. van Breemen is an academic researcher from Oregon State University. The author has contributed to research in topics: Mass spectrometry & High-performance liquid chromatography. The author has an hindex of 67, co-authored 362 publications receiving 14444 citations. Previous affiliations of Richard B. van Breemen include The Hershey Company & University of Illinois at Urbana–Champaign.

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Journal ArticleDOI

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

Aimee L. Eggler, +4 more
- 19 Jul 2005 - 
TL;DR: A model is proposed that should aid in the understanding of Keap1-Nrf2 signaling mechanisms and is tested using a series of ARE inducers, suggesting that the direct disruption model for Keap 1-NRF2 is incorrect.
Journal ArticleDOI

Caco-2 cell permeability assays to measure drug absorption.

Richard B. van Breemen, +1 more
- 16 Aug 2005 - 
TL;DR: Mass spectrometry not only eliminates the need for radiolabelled compounds, but permits the simultaneous measurement of multiple compounds, thereby increasing the throughput of the experiments and facilitating the investigation of the metabolism of compounds by Caco-2 cells.
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Evaluation of Estrogenic Activity of Plant Extracts for the Potential Treatment of Menopausal Symptoms

Jianghua Liu, +11 more
- 24 Mar 2001 - 
TL;DR: Genistein was found to be the most effective of four red clover isoflavones tested in the above in vitro assays, suggesting a potential use for some dietary supplements, ingested by human beings, in the treatment of menopausal symptoms.
Journal ArticleDOI

Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention.

Longwen Chen, +7 more
- 19 Dec 2001 - 
TL;DR: A possible role for a tomato sauce constituent, possibly lycopene, in the treatment of prostate cancer is indicated and warrant further testing with a larger sample of patients, including a control group.
Journal ArticleDOI

Human, rat, and mouse metabolism of resveratrol.

Chongwoo Yu, +9 more
- 01 Dec 2002 - 
TL;DR: The results indicate that trans-resveratrol-3-O-glucuronide and trans-Resver atrol- 3-sulfate are the most abundant metabolites of resveratros, indicating that isomerization was not an important factor in the metabolism and elimination of res veratrol