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Richard H. Schmidt

Researcher at University of Utah

Publications -  95
Citations -  4942

Richard H. Schmidt is an academic researcher from University of Utah. The author has contributed to research in topics: Aneurysm & Subarachnoid hemorrhage. The author has an hindex of 32, co-authored 88 publications receiving 4757 citations. Previous affiliations of Richard H. Schmidt include Harvard University & University of Washington.

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Journal Article

Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation.

TL;DR: The steps involved in the grafting of mesencephalic and septal embryonic tissue in the form of dissociated cell suspensions are described in detail and technical problems and limitations are discussed.
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Origin and termination of the diencephalo-spinal dopamine system in the rat

TL;DR: In agreement with the biochemical data the fluorescence histochemistry shows that the spinal dopamine innervation is mainly confined to the dorsal horn, the intermediolateral cell column and associated parts of the intermediate and central gray, and suggests that the diencephalic A11 cell group is the principal, and perhaps exclusive, source of this innervation.
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Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra.

TL;DR: The use of dissociated brain tissue preparations permits reliable intraparenchymal grafting of neurones to plausibly any desired site within the central nervous system, and should open entirely new possibilities for investigation of neuronal growth dynamics and functional reconstruction of damaged brain circuits, perhaps even in brains of larger mammals.
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Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage

TL;DR: Shunting of CSF through a lumbar drain after an SAH markedly reduces the risk of clinically evident vasospasm and its sequelae, shortens hospital stay, and improves outcome.
Journal Article

Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites.

TL;DR: The results indicate that nigral suspension grafts can be at least as effective as solid grafts in reversing the functional deficits induced by dopamine denervation, provided that placements are selected within appropriate dopamine terminal regions of the forebrain (e.g. caudate-putamen or nucleus accumbens).