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Richard J. Wurtman
Researcher at Massachusetts Institute of Technology
Publications - 933
Citations - 54523
Richard J. Wurtman is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Choline & Melatonin. The author has an hindex of 114, co-authored 933 publications receiving 53290 citations. Previous affiliations of Richard J. Wurtman include Boston Children's Hospital & Albert Einstein College of Medicine.
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Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids
TL;DR: The main determinant of brain tryPTophan and serotonin concentrations does not appear to be plasma tryptophan alone, but the ratio of this amino acid to other plasma neutral amino acids that compete with it for uptake into the brain.
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Brain serotonin content: physiological dependence on plasma tryptophan levels.
TL;DR: Brain serotonin cocentrations at 1 p.m. were significantly elevated 1 hour after rats received a dose of L-tryptophan and plasma and brain tryptophan levels were elevated 10 to 60 minutes after the injection, but they never exceeded the concentrationis that occur nocturnally in untreated aninmals as result of their normal 24-hour rhythms.
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A sensitive and specific assay for the estimation of monoamine oxidase.
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Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors
TL;DR: Stimulation of m1 and m3 receptor subtypes with carbachol increased the basal release of APP derivatives within minutes of treatment, indicating that preexisting APP is released in response to receptor activation and protein kinases mediate neurotransmitter receptor-controlled APP processing.
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The pineal gland.
TL;DR: It is not yet certain what pbysiobgical~dependontbepineal clock for cues is, but there is evidence at band ~ggest that the pineal participates in sanewayintbequlationoftbegonads,orsexglands.