R
Richard M. W. Hoetelmans
Researcher at Tibotec
Publications - 99
Citations - 5057
Richard M. W. Hoetelmans is an academic researcher from Tibotec. The author has contributed to research in topics: Ritonavir & Darunavir. The author has an hindex of 40, co-authored 96 publications receiving 4950 citations. Previous affiliations of Richard M. W. Hoetelmans include Netherlands Cancer Institute & Boston Children's Hospital.
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Journal ArticleDOI
Darunavir: pharmacokinetics and drug interactions.
TL;DR: Reports from resource-limited countries suggest that initial ART programmes are as effective as in resource-rich countries, which should limit HIV drug resistance if programme effectiveness continues during scale-up.
Journal ArticleDOI
Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study.
Pythia T. Nieuwkerk,Mirjam A. G. Sprangers,David M. Burger,Richard M. W. Hoetelmans,P.W.H. Hugen,Sven A. Danner,Marchina E. van der Ende,Margriet M. E. Schneider,Gerrit Schrey,Pieter L. Meenhorst,Herman G. Sprenger,R.H. Kauffmann,Marielle Jambroes,Margaret A. Chesney,Frank de Wolf,Joep M. A. Lange +15 more
TL;DR: In this article, adherence to highly active antiretroviral therapy (HAART) for human immunodeficiency syndrome type 1 (HIV-1) infection is investigated among patients in a clinical cohort study.
Journal ArticleDOI
High exposure to nevirapine in plasma is associated with an improved virological response in HIV-1-infected individuals.
A.I. Veldkamp,Gerrit Jan Weverling,Joep M. A. Lange,Julio S. G. Montaner,Peter Reiss,David A. Cooper,Stefano Vella,David A. Hall,Jos H. Beijnen,Richard M. W. Hoetelmans +9 more
TL;DR: A high exposure to nevirapine (in a twice daily regimen) is significantly associated with improved virological response in the short as well as in the long term, suggesting that optimization of ne virapine concentration might be used as a tool to improve virologic outcome in (antiretroviral-naive) patients treated with nevirAPine.
Journal ArticleDOI
Therapeutic drug monitoring in HIV infection: current status and future directions.
David Back,Giorgio Gatti,Courtney V. Fletcher,Rodolphe Garaffo,Richard Haubrich,Richard M. W. Hoetelmans,Michael Kurowski,Andrew D. Luber,Concepta Merry,Carlo Federico Perno +9 more
TL;DR: This article will guide the reader through the data and discussions that have allowed the panel to formulate a series of position statements regarding the current status and future applications of TDM in antiretroviral therapy to provide suggestions for the design of future TDM clinical trials.