Ríos A

TL;DR: Ten characteristics of bone marrow biopsies in paraffin sections obtained at diagnosis from patients with myelodysplastic syndromes classified according to the FAB criteria were analysed to identify both the most relevant morphologic data and any possible influence on survival.

TL;DR: The results show that BMMC from both healthy controls and HM patients display a relatively heterogenous immunophenotype, which is similar but heterogenous to bone marrow mast cells from other tissues.

TL;DR: The assessment of the quantitative expression of cell-adhesion molecules and growth-factor receptors together with cell cycle studies of mast cells could be of value for monitoring therapy and predicting clinical outcome in aggressive SMCD.

TL;DR: Clinical, biological, and immunophenotypical characteristics of B-cell chronic lymphocytic leukemia patients with trisomy 12 detected by fluorescence in situ hybridization (FISH) using a chromosome 12 alpha-centromeric probe (D12Z3) were analyzed and significant associations were found between the percentage of trisomic cells and both the WBC count and the PB lymphocytes.

TL;DR: Multivariate regression analysis demonstrated that the combination of three clinicopathologic characteristics (bone marrow histopathologic pattern, absolute peripheral blood lymphocyte count, and the presence or not of hypogammaglobulinaemia) had the strongest predictive relationship with survival time.