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Rita G. Hazell

Researcher at Aarhus University

Publications -  166
Citations -  4946

Rita G. Hazell is an academic researcher from Aarhus University. The author has contributed to research in topics: Crystal structure & Catalysis. The author has an hindex of 37, co-authored 166 publications receiving 4841 citations. Previous affiliations of Rita G. Hazell include National Research Foundation of South Africa.

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Organocatalytic Asymmetric Conjugate Addition of Nitroalkanes to α,β-Unsaturated Enones Using Novel Imidazoline Catalysts

TL;DR: In this paper, a new catalytic enantioselective conjugate addition of nitroalkanes to acyclic α,β-unsaturated enones catalyzed by novel organic catalysts has been developed.
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Copper-Catalyzed Enantioselective Henry Reactions of α-Keto Esters: An Easy Entry to Optically Active β-Nitro-α-hydroxy Esters and β-Amino-α-hydroxy Esters

TL;DR: The catalytic enantioselective Henry reaction of α-keto esters with nitromethane has been developed in this article, where the reaction conditions have been optimized by the screening of different chiral Lewis acids, solvents, and bases, and it was found that the copper(II)−tert-butyl bisoxazoline complex in combination with triethylamine catalyzed a highly enanti-lective reaction giving optically active β-nitro-α-hydroxy esters in high yields and with excellent enantiomeric excess
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Catalytic, highly enantioselective Friedel-Crafts reactions of aromatic and heteroaromatic compounds to trifluoropyruvate. A simple approach for the formation of optically active aromatic and heteroaromatic hydroxy trifluoromethyl esters.

TL;DR: A new catalytic enantioselective synthetic method for the formation of optically active aromatic and heteroaromatic hydroxy-trifluoromethyl ethyl esters is presented, which proceeds in good yield and with high enantiomeric excess.