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Robert A. Levine
Researcher at Harvard University
Publications - 666
Citations - 37467
Robert A. Levine is an academic researcher from Harvard University. The author has contributed to research in topics: Mitral valve & Mitral regurgitation. The author has an hindex of 94, co-authored 630 publications receiving 34931 citations. Previous affiliations of Robert A. Levine include Cornell University & State University of New York System.
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Journal ArticleDOI
Filamin-A as a Balance between Erk/Smad Activities During Cardiac Valve Development.
Katelynn Toomer,Kimberly Sauls,Diana Fulmer,Lilong Guo,Kelsey Moore,Janiece Glover,Rebecca Stairley,Joyce Bischoff,Robert A. Levine,Russell A. Norris +9 more
TL;DR: In vivo and in vitro studies have validated genetic findings and revealed FLNA as a central regulator of valve morphogenesis and support Filamin‐A as a protein that regulates the balance between Erk and Smad activation and an inability of Filamin-A deficient valve interstitial cells to effectively remodel the increased ECM production through a β1‐integrin mechanism.
Journal ArticleDOI
Mitral Annular Dynamics in AF Versus Sinus Rhythm: Novel Insights Into the Mechanism of AFMR.
Sébastien Deferm,Philippe Bertrand,David Verhaert,Frederik H. Verbrugge,Jeroen Dauw,Kevin Thoelen,Alexander Giesen,Liesbeth Bruckers,Filip Rega,James D. Thomas,Robert A. Levine,Pieter M. Vandervoort +11 more
TL;DR: In this article, the authors investigated mitral annulus dynamics in atrial fibrillation and after sinus rhythm restoration, and assessed the relationship between annular dynamics and mitral regurgitation.
Journal ArticleDOI
Assessment of left ventricular volume and function by integration of simplified 3D echocardiography, tissue harmonic imaging and automated extraction of endocardial borders.
Donato Mele,Roberta Teoli,Corrado Cittanti,Giovanni Pasanisi,Gabriele Guardigli,Robert A. Levine,Roberto Ferrari +6 more
TL;DR: THI permits accurate 3D reconstruction of LV borders detected by DEQ, allowing automated VTC throughout the cardiac cycle as well as study of LV remodelling.
Journal ArticleDOI
Contexts and culture in psychological research.
TL;DR: This volume outlines a new methodology of achievement motivation, an approach that seeks to indentify the cultural and personal meanings of educational performance through methods that clarify its multiple contexts.
Journal ArticleDOI
Mitral Valve Prolapse Patients with Less than Moderate Mitral Regurgitation Exhibit Early Cardiac Chamber Remodeling.
Li Tan Yang,So Woon Ahn,Zhenhua Li,Giovanni Benfari,Rekha Mankad,Masaaki Takeuchi,Robert A. Levine,Maurice Enriquez-Sarano,Hector I. Michelena +8 more
TL;DR: Patients with less than moderate MR due to MVP exhibit early LV and LA remodeling, which does not predict MR progression or mortality, while female sex and MVP (vs controls) were protective factors for mortality.