R
Robert J. Mcenroe
Researcher at Roche Diagnostics
Publications - 5
Citations - 234
Robert J. Mcenroe is an academic researcher from Roche Diagnostics. The author has contributed to research in topics: Analyte & Substrate (chemistry). The author has an hindex of 4, co-authored 5 publications receiving 234 citations.
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Patent
Osmium-containing redox mediator
Zhi David Deng,Gerald F. Sigler,Nigel A. Surridge,Christopher D. Wilsey,Robert J. Mcenroe,Walter Jernigan,Rebecca W. Muddiman +6 more
TL;DR: A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors is presented in this article, which are particularly useful as a component of a reagent for measuring analytes from a biological fluid, such as blood.
Patent
Reagent including an osmium-containing redox mediator
Zhi David Deng,Gerald F. Sigler,Nigel A. Surridge,Christopher D. Wilsey,Robert J. Mcenroe,Walter Jernigan,Rebecca W. Muddiman +6 more
TL;DR: A new group of Os(II) and Os(III) compounds were proposed in this paper, which are useful as redox mediators in electrochemical biosensors, where they have low oxidation potential, fast reaction kinetics between the electroactive center of an enzyme and the compound, slow oxidation of osmium by oxygen, and excellent solubility in aqueous medium.
Patent
An electrochemical enzymatic complementation immunoassay
Mary Brown,Lance S. Kuhn,Robert J. Mcenroe,Rebecca W. Muddiman,M Ochs,John G.R. Hurrell,Hans-Joachim Guder +6 more
TL;DR: An immunoassay diagnostic kit, method, and apparatus for electrochemically determining the concentration of an analyte in a sample is described in this paper, where the analyte and the enzyme-donor polypeptide conjugate competitively bind to the antibody and the active enzyme hydrolyzes the labeled substrate, resulting in the generation of an electroactive label which can then be oxidized at the surface of an electrode.
Patent
Electrochemical enzyme assay
Mary Brown,Harvev Buck,Hans-Joachim Guder,John G.R. Hurrell,Lance S. Kuhn,Robert J. Mcenroe,Rebecca W. Muddiman,Mary Luann Ochs +7 more
TL;DR: In this paper, a diagnostic kit, method, and apparatus for electrochemically determining the presence or concentration of an analyte in a sample is presented. But, their method is limited to the presence of a single analyte.
Patent
Mediateur redox contenant de l'osmium
Zhi David Deng,Gerald F. Sigler,Nigel A. Surridge,Christopher D. Wilsey,Robert J. Mcenroe,Walter Jernigan,Rebecca W. Muddiman +6 more
TL;DR: In this paper, a nouveau groupe de composes a base d'osmium (II) and osmium (III) efficaces en tant que mediateurs redox dans des biocapteurs electrochimiques.