The hepatitis B virus (HBV), discovered in 1966, infects more than 350 million people worldwide.1 Hepatitis B is a leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma, accounting for 1 million deaths annually. Knowledge of the intricacies of viral infection and of the molecular biology of this fascinating virus has led to the successful development of a vaccine and to treatment sometimes capable of eradicating chronic infection. This review addresses many aspects of HBV infection, including the role of the immune system in determining the outcome of clinical infection, recent developments in molecular studies of the virus, and new . . .

Hepatitis B virus infection.

Mise a jour: anatomopathologie, anomalies immunologiques et pathogenese, tests de laboratoire, manifestations cliniques et troubles associes, evolution, traitement

Primary biliary cirrhosis.

Drug-induced hepatotoxicity.

https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.22906

Primary Biliary Cirrhosis

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.1840120505

Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors.

Tumors of the Liver and Intrahepatic Bile Ducts

Clinical and pathologic features of 23 patients with a distinctive histologic and clinical variant of hepatocellular carcinoma are summarized. The variant pattern of hepatocellular carcinoma is most common in the age group 5--35 years and occurs equally in either sex. The distinctive histologic features include 1) deeply eosinophilic neoplastic hepatocytes, many of which contain intracytoplasmic hyaline globules and distinct pale bodies and 2) fibrosis arranged in a lamellar fashion around the neoplastic hepatocytes. The histologic and gross features of the tumor have been confused both with focal nodular hyperplasia and with hepatocellular adenoma. The average survival of 32 months and the high operability rate of 48% far exceed the survival or operability for ordinary hepatocellular carcinoma. Thus, this tumor type must be recognized and considered separately when evaluating therapeutic results in large series of patients with hepatocellular carcinoma.

Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features.

Excerpt Hydrothorax has long been recognized as a complication of cirrhosis, but there has been much speculation as to its origin. Higgins and his colleagues (1) suggested it forms from the plasma ...

Pathogenesis and treatment of hydrothorax complicating cirrhosis with ascites.

https://www.gastrojournal.org/article/S0016-5085(84)80153-5/pdf

Fulminant B viral hepatitis: role of delta agent.

Serums from 55 patients with primary hepatocellular carcinoma were examined for the presence of hepatitis-associated antigen (HAA). Forty-four (80%) had the antigen in their serums; alpha ...

Robert L. Peters

Papers

Tumors of the Liver and Intrahepatic Bile Ducts

Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features.

Pathogenesis and treatment of hydrothorax complicating cirrhosis with ascites.

Fulminant B viral hepatitis: role of delta agent.

Hepatitis-associated antigen and hepatocellular carcinoma in Taiwan.