Showing papers in "Annals of Internal Medicine in 1971"
TL;DR: Risk of coronary heart disease over 14 years was examined prospectively in 2,282 men and 2,845 women according to their antecedent cholesterol and lipoprotein status.
Abstract: Abstract Risk of coronary heart disease over 14 years was examined prospectively in 2,282 men and 2,845 women according to their antecedent cholesterol and lipoprotein status. An increased risk pro...
2,044 citations
379 citations
TL;DR: Infection with Candida albicans develops in diverse clinical settings and may be minimal or life-threatening in severity, depending on the site of infection and clinical circumstance.
Abstract: Infection withCandida albicansdevelops in diverse clinical settings. It may be minimal or life-threatening in severity, depending on the site of infection and clinical circumstance. Chroni...
353 citations
TL;DR: The recent marked increase in incidence of gonorrhea prompted this analysis of the systemic manifestations of gonococcal infection, and of 42 patients with disseminated infection, 79% were women.
Abstract: The recent marked increase in incidence of gonorrhea prompted this analysis of the systemic manifestations of gonococcal infection. Of 42 patients with disseminated infection, 79% were wom...
350 citations
TL;DR: A prospective study of patients admitted to a hospital where there was endemic nosocomial infection with multidrug-resistant klebsiella was undertaken to evaluate the role of intestinal col...
Abstract: Excerpt A prospective study of patients admitted to a hospital where there was endemic nosocomial infection with multidrug-resistant klebsiella was undertaken to evaluate the role of intestinal col...
336 citations
327 citations
TL;DR: Severe hyponatremia secondary to the use of diuretics was observed in 25 nonedematous patients with clinically normal hydration and creatinine clearances.
Abstract: Severe hyponatremia (serum Na, 91 to 120 mEq/liter) secondary to the use of diuretics was observed in 25 nonedematous patients with clinically normal hydration and creatinine clearances; i...
324 citations
TL;DR: In this chapter, Ellenberg describes a study undertaken to investigate the influence of endocrine, neurologic, and urologic factors in the etiology of impotence in diabetic males.
Abstract: In this chapter, Ellenberg describes a study undertaken to investigate the influence of endocrine, neurologic, and urologic factors in the etiology of impotence in diabetic males. Accurate diagnosis of the basis for diabetic impotence is crucial, as diagnosis determines which treatment strategies are indicated and what the prognosis for reversal will be.
273 citations
TL;DR: A large-scale epidemiologic study of scleroderma was completed, including 86 patients who met specified criteria and who were hospital-diagnosed from 1947 through 1968, finding no significant differences in the number of patients diagnosed with the disease or their prognosis.
Abstract: A large-scale epidemiologic study of scleroderma was completed, including 86 patients who met specified criteria and who were hospital-diagnosed from 1947 through 1968. The average annual ...
261 citations
236 citations
TL;DR: A marked reduction in red cell glucose utilization, lactate production, and 2-3-diphosphoglycerate and adenosine triphosphate concentration occurred in a patient with intractable diarrhea.
Abstract: A marked reduction in red cell glucose utilization, lactate production, and 2,3-diphosphoglycerate and adenosine triphosphate concentration occurred in a patient with intractable diarrhea ...
TL;DR: Of 441 consecutive patients admitted to a coronary care unit, 145 (32.7%) were referred for psychiatric consultation, and the three most frequent reasons for referral were anxiety, depres...
Abstract: Of 441 consecutive patients admitted to a coronary care unit, 145 (32.7%) were referred for psychiatric consultation. The three most frequent reasons for referral were anxiety (47), depres...
TL;DR: Serums from 55 patients with primary hepatocellular carcinoma were examined for the presence of hepatitis-associated antigen (HAA), and forty-four had the antigen in their serums.
Abstract: Serums from 55 patients with primary hepatocellular carcinoma were examined for the presence of hepatitis-associated antigen (HAA). Forty-four (80%) had the antigen in their serums; alpha ...
TL;DR: The intracellular concentration of phosphoribosylpyrophosphate, a high-energy 1,5-substituted ribose sugar, has been demonstrated to have a critical role in the regulation of purine levels in the cell.
Abstract: The intracellular concentration of phosphoribosylpyrophosphate (PRPP), a high-energy 1,5-substituted ribose sugar, has been demonstrated to have a critical role in the regulation of purine...
TL;DR: 36 of 325 women referred for plasma renin activity and aldosterone studies over a 4 year period were using oral contraceptives and 20 were taking conjugated estrogens, and available medical records indicated that 22 of the contraceptive users and 5 of the estrogen users were normotensive before medication.
Abstract: Twenty-two patients developed hypertension on oral contraceptive pills. Mean blood pressure of the group before, during, and after the medication was stopped was 125/76, 183/110, and 130/8...
TL;DR: Forty patients with acute leukemia were treated with Intravenous L-asparaginase in doses ranging from 10 to 1,000 international units/kg body weight per day for 2 to 20 days.
Abstract: Forty patients with acute leukemia were treated with Intravenous L-asparaginase in doses ranging from 10 to 1,000 international units/kg body weight per day for 2 to 20 days. Most had long...
TL;DR: Thirteen women with lupus nephritis were hospitalized for a 10-week double-blind therapeutic trial comparing oral cyclophosphamide with placebo, finding that concurrent corticosteroid therapy, up to 30...
Abstract: Thirteen women with lupus nephritis were hospitalized for a 10-week double-blind therapeutic trial comparing oral cyclophosphamide with placebo. Concurrent corticosteroid therapy, up to 30...
TL;DR: Two groups of hypertensive patients were divided into two groups by measuring their plasma renin activity (PRA) after 4 hours in an upright posture, and eight patients with low PRA and a low high PRA were selected.
Abstract: Twenty-three hypertensive patients were divided into two groups by measuring their plasma renin activity (PRA) after 4 hours in an upright posture Eight patients with low PRA and a low al
TL;DR: The sensitivity of certain laboratory tests used to screen patients for pulmonary embolism was assessed in a prospective study of 50 patients and showed positive results for several tests.
Abstract: Many different laboratory tests have been used to screen patients for pulmonary embolism. The sensitivity of certain laboratory tests was assessed in a prospective study of 50 patients wit...
TL;DR: The normal human serum thyrotrophin measured by a double antibody radioimmunoassay was 3.9 ± 2.0 (SD) µunits/ml, which was markedly elevated in 61 patients with primary hypothyroidism a year ago.
Abstract: The normal human serum thyrotrophin (TSH) measured by a double antibody radioimmunoassay was 3.9 ± 2.0 (SD) µunits/ml. It was markedly elevated in 61 patients with primary hypothyroidism a...
TL;DR: In this article, 12 persons working in the manufacture or grinding of tungsten carbide developed a progressive diffuse interstitial pneumonia, characterized clinically by nonproductive cough and by dys...
Abstract: Twelve persons working in the manufacture or grinding of tungsten carbide developed a progressive diffuse interstitial pneumonia, characterized clinically by nonproductive cough and by dys...
TL;DR: This data indicates that suppression of salivary gland prolapse in patients with Sjogren's syndrome is a major cause of death and the use of chemotherapy to treat the disease is a viable option.
Abstract: Recent advances in the study of Sjogren's syndrome include detection of antisalivary duct antibody (ASDA) in patients' sera, development of sensitive techniques to evaluate salivary glandu...
TL;DR: Patients with classical systemic lupus erythematosus and joint manifestations are studied to characterize features of the arthritis that may suggest this diagnosis.
Abstract: We have studied 25 patients with classical systemic lupus erythematosus and joint manifestations to characterize features of the arthritis that may suggest this diagnosis. Objective arthri...
TL;DR: The role of anaerobic bacteria in the etiology of pyogenic liver abscess has not been fully recognized and the number of cases encountered in 11 years represents a large number.
Abstract: The role of anaerobic bacteria in the etiology of pyogenic liver abscess has not been fully recognized. In 11 years we have encountered 25 cases of anaerobic liver abscess, which represent...