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Showing papers by "Robert L. Reid published in 2002"


Journal ArticleDOI
TL;DR: Transient inhibition of aromatases activity in the early follicular phase with the aromatase inhibitor letrozole results in stimulation of ovarian folliculogenesis similar to that seen with clomiphene citrate with no apparent adverse effect on endometrial thickness or pattern at midcycle.

326 citations


Journal ArticleDOI
TL;DR: The findings of the Women's Health Initiative study can be applied to reach appropriate clinical decisions and the most common indication for hormone replacement therapy is menopausal symptoms, for which it is effective, not prevention of disease.
Abstract: The recent Women's Health Initiative study report evaluated the long-term benefits and risks of hormone replacement therapy among healthy postmenopausal women. The report showed that the risk-benefit profile of continuous combined hormone replacement therapy was not consistent with the primary Prevention of coronary heart disease. The Women's Health Initiative study of continuous combined hormone replacement therapy is a landmark study and the results provide valuable information for patients and clinicians. However, the most common indication for hormone replacement therapy is menopausal symptoms, for which it is effective, not prevention of disease and the most common use is for less than three years. Nevertheless, even short-term use has small effects on some outcomes. This statement discusses how the findings of the Women's Health Initiative study can be applied to reach appropriate clinical decisions.

20 citations


Journal ArticleDOI
TL;DR: Systemic ALA followed by exposure to photoactivating light at relatively low power densities for periods as brief as 10 minutes resulted in ablation of endometriotic explants.

14 citations


Journal ArticleDOI
TL;DR: The controversy over whether young healthy women should discontinue oral contraceptive use before major surgical procedures that are associated with immobility is reflected by a lack of consensus among gynecologists in Canada.

11 citations





Journal ArticleDOI
TL;DR: Le rapport a demontre que le profl des risques-bien-faits de l'hormonotherapie substitutive combinee et continue n'etait pas conforme a la prevention primaire de the cardiopathie ischemique.
Abstract: Resume Le rapport recent de l'etude Women's Health Initiative a evalue les bienfaits et les risques a long terme de l'hormonotherapie substitutive chez les femmes post-menopausees en sante. Le rapport a demontre que le profl des risques-bien-faits de l'hormonotherapie substitutive combinee et continue n'etait pas conforme a la prevention primaire de la cardiopathie ischemique. L'etude Women's Health Initiative de l'hormono-therapie substitutive combinee et continue est une etude marquante et les resultats fournissent des renseignements pertinents aux patientes et aux cliniciens. Par contre, les symptomes de la menopause, et non la prevention de la maladie constituent l'indication la plus commune de l'hormonotherapie substitutive, pour lesquels elle est efficace; de plus, la duree d'emploi la plus commune est de moins de trois ans. Toutefois meme l'emploi a court terme entraine des effets au niveau de certaines issues. Cette declaration discute de l'application des resultats de l'etude Women's Health Initiative dans le but de prendre des decisions cliniques appropriees.

1 citations