R
Robin E. Rutherford
Researcher at Emory University
Publications - 22
Citations - 2155
Robin E. Rutherford is an academic researcher from Emory University. The author has contributed to research in topics: Colorectal adenoma & Vitamin D and neurology. The author has an hindex of 13, co-authored 21 publications receiving 1855 citations. Previous affiliations of Robin E. Rutherford include University of Georgia.
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Journal ArticleDOI
A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant Depression The Role of Baseline Inflammatory Biomarkers
Charles L. Raison,Robin E. Rutherford,Bobbi J. Woolwine,Chen Shuo,Pamela J. Schettler,Daniel Drake,Ebrahim Haroon,Andrew H. Miller +7 more
TL;DR: This proof-of-concept study suggests that TNF antagonism does not have generalized efficacy in treatment-resistant depression but may improve depressive symptoms in patients with high baseline inflammatory biomarkers.
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Effects of Supplemental Vitamin D and Calcium on Oxidative DNA Damage Marker in Normal Colorectal Mucosa: A Randomized Clinical Trial
Veronika Fedirko,Roberd M. Bostick,Qi Long,W. Dana Flanders,Marjorie L. McCullough,Eduard Sidelnikov,Carrie R. Daniel,Robin E. Rutherford,Aasma Shaukat +8 more
TL;DR: Preliminary results indicate that calcium and vitamin D3 may decrease oxidative DNA damage in the normal human colorectal mucosa, and support the hypothesis that 8-OH-dG labeling in colOREctal crypts is a treatable oxidative DNADamage biomarker of risk for coloreCTal neoplasms, and provide support for further investigation of calcium anditamin D3 as chemopreventive agents against colorectorial neoplasm.
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Effects of vitamin D and calcium supplementation on markers of apoptosis in normal colon mucosa: a randomized, double-blind, placebo-controlled clinical trial.
Veronika Fedirko,Roberd M. Bostick,W. Dana Flanders,Qi Long,Aasma Shaukat,Robin E. Rutherford,Carrie R. Daniel,Vaunita Cohen,Chiranjeev Dash +8 more
TL;DR: It is suggested that calcium and vitamin D, individually or together, may enhance apoptosis in the normal human colorectal epithelium, and the strongest treatment effects may be vitamin D related and in the upper sections of the coloreCTal crypts.
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Effects of vitamin d and calcium on proliferation and differentiation in normal colon mucosa: a randomized clinical trial.
Veronika Fedirko,Roberd M. Bostick,W. Dana Flanders,Qi Long,Eduard Sidelnikov,Aasma Shaukat,Carrie R. Daniel,Robin E. Rutherford,Jill Woodard +8 more
TL;DR: It is indicated that calcium and vitamin D promote colorectal epithelial cell differentiation and may “normalize” the coloreCTal crypt proliferative zone in sporadic adenoma patients, and support further investigation of calcium anditamin D as chemopreventive agents against colorectoral neoplasms.
Journal ArticleDOI
Colorectal Cancer Initial Diagnosis: Screening Colonoscopy, Diagnostic Colonoscopy, or Emergent Surgery, and Tumor Stage and Size at Initial Presentation.
Courtney C. Moreno,Pardeep Mittal,Patrick S. Sullivan,Robin E. Rutherford,Charles A. Staley,Kenneth Cardona,Natalyn Hawk,W. Thomas Dixon,Hiroumi D. Kitajima,Jian Kang,William Small,John N. Oshinski,John R. Votaw +12 more
TL;DR: Nearly 90% of colorectal cancer patients were diagnosed after development of symptoms and had more advanced disease than asymptomatic screening patients.