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Robin W. Justice

Researcher at University of California, Irvine

Publications -  8
Citations -  1277

Robin W. Justice is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Cell type & Tumor suppressor gene. The author has an hindex of 7, co-authored 8 publications receiving 1189 citations. Previous affiliations of Robin W. Justice include Claremont McKenna College.

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The Drosophila Tumor Suppressor Gene Warts Encodes a Homolog of Human Myotonic Dystrophy Kinase and Is Required for the Control of Cell Shape and Proliferation

TL;DR: The results raise the possibility that homozygous loss of the myotonic dystrophy kinase may contribute to the development of multiple pilomatrixomas and with other tumors including neurofibromas and parathyroid adenomas.
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The Anopheles gambiae odorant binding protein 1 (AgamOBP1) mediates indole recognition in the antennae of female mosquitoes.

TL;DR: This case represents the first documented instance of a specific A. gambiae OBP–ligand pairing combination, demonstrates the significance of OBPs in odor recognition, and can be expanded to the identification of other ligands for OBPs of Anopheles and other medically important insects.
Journal ArticleDOI

Drosophila in cancer research: the first fifty tumor suppressor genes.

TL;DR: The neurogenic mutants, including Notch, show conversion of epidermal cells to neuroblasts, leading to the ‘neurogenic’ phenotype of excess nervous tissue, supporting indications from human cancer that cadherins play an important role in tumor suppression.
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Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila.

TL;DR: Recent work on the molecular identification of tumor suppressor genes that function in two different cell types of the Drosophila larva: the blood cells, and the undifferentiated epithelial cells of developing imaginal discs is described.
Patent

Methods to utilize invertebrate chemosensory proteins for industrial and commercial uses

TL;DR: In this article, the authors provide methods and compositions for using chemosensory proteins derived from invertebrates to bind or detect specific compounds, such as odorant binding proteins (OBPs), sensory appendage proteins (SAPs), orthologs of the Drosophila melanogaster Takeout protein (TOLs), odorant or gustatory receptors (ORs, GRs, or collectively GPCRs), other serpentine receptors, and odorant degrading enzymes (ODEs).