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Rodney L. Biltonen

Researcher at University of Virginia

Publications -  99
Citations -  6020

Rodney L. Biltonen is an academic researcher from University of Virginia. The author has contributed to research in topics: Lipid bilayer & Vesicle. The author has an hindex of 41, co-authored 99 publications receiving 5917 citations. Previous affiliations of Rodney L. Biltonen include Johns Hopkins University School of Medicine & University of Virginia Health System.

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A calorimetric and fluorescent probe study of the gel-liquid crystalline phase transition in small, single-lamellar dipalmitoylphosphatidylcholine vesicles.

TL;DR: An experimentally testable thermodynamic and kinetic model based upon the results of a calorimetric and fluorescent probe study of the thermotropic behavior of various types of dispersions of dipalmitolphosphatidylcholine bilayer vesicles is developed.
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The use of differential scanning calorimetry as a tool to characterize liposome preparations

TL;DR: Differential scanning calorimetry (DSC) as discussed by the authors measures the temperature-dependence of the excess heat capacity of a system due to thermal phase transitions, which can serve as a powerful tool for quality control of liposomes.
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Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems

TL;DR: The theoretical basis for the statistical mechanical deconvolution of a thermally induced macromolecular melting profile is presented in this article, where it is shown that all the thermodynamic quantities characterizing a multistate MC transition can be obtained from the average excess enthalpy function of the system, without any assumption of the particular model or mechanism of the reaction.
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Studies on the anomalous thermotropic behavior of aqueous dispersions of dipalmitoylphosphatidylcholine-cholesterol mixtures

TL;DR: Examination of the thermotropic behavior of aqueous dispersions of dipalmitoylphosphatidylcholine-cholesterol mixtures by high-sensitivity scanning calorimetry has revealed that the phospholipid gel to liquid-crystalline phase transition consists of two components.
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Enthalpy-entropy compensation and heat capacity changes for protein-ligand interactions: general thermodynamic models and data for the binding of nucleotides to ribonuclease A.

TL;DR: Experimental thermodynamic data for the binding of cytidine 3'-phosphate to ribonuclease A demonstrate apparent enthalpy-entropy compensation when pH and ionic strength are varied.