Rodolfo Chavez-Dominguez

TL;DR: The role of hypoxia as a mechanism that drives the acquisition of tumor hallmarks that make certain cancers more aggressive is discussed and some combinations of therapies that inhibit the angiogenesis process and that may be a successful strategy for cancer patients are indicated.

TL;DR: A broad view of the participation of autophagy in distinct phases of tumor development, including participation in important cellular processes such as cell death, metabolic reprogramming, metastasis, immune evasion and treatment resistance that all contribute to tumor development is presented.

TL;DR: Based on the cancer immunoediting concept, a rigorous and regulated inflammation process triggers participation of innate and adaptive immune responses for efficient elimination of transformed cells, an equilibrium phase is induced as mentioned in this paper.

TL;DR: This review aims to provide a succinct overview of the involvement of cancer-related inflammation at the local and systemic level throughout tumor development and the emergence of some paraneoplastic syndromes and their main clinical manifestations.

TL;DR: In this paper , the authors discuss the role of the immune checkpoints in recognizing and eliminating tumor cells and how the gradual metabolic changes in the TME alter their antitumor functions.