R
Roger J. Pomerantz
Researcher at Thomas Jefferson University
Publications - 166
Citations - 8695
Roger J. Pomerantz is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Viral replication & Virus. The author has an hindex of 48, co-authored 166 publications receiving 8425 citations. Previous affiliations of Roger J. Pomerantz include Allegheny University of the Health Sciences & Rockefeller University.
Papers
More filters
Journal ArticleDOI
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
TL;DR: It is demonstrated that CEM15, an endogenous inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, is a cytidine deaminase and is able to induce G to A hypermutation in newly synthesized viral DNA, which could account for the Vif-defective phenotype.
Journal ArticleDOI
The challenge of finding a cure for HIV infection.
Douglas D. Richman,David M. Margolis,Martin Delaney,Warner C. Greene,Daria J. Hazuda,Roger J. Pomerantz +5 more
TL;DR: The current understanding of suppressive antiretroviral therapy, the latent viral reservoir, and the needs for and challenges of attacking this reservoir to achieve a cure are discussed.
Journal ArticleDOI
Antiviral Potentials of Medicinal Plants
Muhammad Mukhtar,Mohammad Arshad,Mahmood Ahmad,Roger J. Pomerantz,Brian Wigdahl,Zahida Parveen +5 more
TL;DR: Potential antiviral properties of medicinal plants against a diverse group of viruses are described, and screening the potential of plants possessing broad-spectrum antiviral effects against emerging viral infections is suggested.
Journal ArticleDOI
Twenty years of therapy for HIV-1 infection
Roger J. Pomerantz,David Horn +1 more
TL;DR: This article summarizes the accomplishments thus far and what lies ahead in the struggle to improve the treatment of, and possibly eliminate, HIV-1 infection.
Journal ArticleDOI
Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis in Human Neuronal Cells
TL;DR: Analysis of the apoptotic effects of the HIV-1 Vpr protein on the human neuronal precursor NT2 cell line at a range of concentrations suggests that extracellular Vpr, along with other lentiviral proteins, may increase neuronal apoptosis in the CNS.