Roland Stein

TL;DR: Antibodies like A1 and 7G2 could improve targeted therapy in ovarian cancer not only by specifically labeling overexpressed antigens but also by blocking adenosine-dependent immune evasion in this immunogenic malignancy.

TL;DR: Adenosine generated by OvCA cells likely contributes to the recruitment of TAMs which further amplify adenosine-dependent immunosuppression via additional ectonucleotidase activity, which could improve immune responses in ovarian cancer.

TL;DR: An unanticipated targeting of stem cell-like breast cancer cells by T-DM1 is revealed that may contribute to the clinical efficacy of this recently approved antibody-drug conjugate.

TL;DR: The bottom line of different mathematical models is the prior importance of subcategories of breast cancer and the age at primary diagnosis for the appearance of osseous metastases.

TL;DR: This multicentered health services research approach demonstrates that predicting tumor size by mammography and ultrasound provides accurate results.