R
Rolf D. Walter
Researcher at Bernhard Nocht Institute for Tropical Medicine
Publications - 156
Citations - 4645
Rolf D. Walter is an academic researcher from Bernhard Nocht Institute for Tropical Medicine. The author has contributed to research in topics: Onchocerca volvulus & Plasmodium falciparum. The author has an hindex of 40, co-authored 156 publications receiving 4489 citations.
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Thiol-based redox metabolism of protozoan parasites
TL;DR: The review considers redox enzymes of Plasmodium spp.
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Targeting polyamines of parasitic protozoa in chemotherapy.
TL;DR: The current status of research into drugs that exploit polyamine metabolism of trypanosomatid and malaria parasites, and proposed priorities for research into such drugs are summarized.
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Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display
TL;DR: The steady-state mRNA levels of the manganese-type and the copper/zinc-type SODs increased 2-fold in the larval population in response to paraquat, whereas mixed stage populations did not show any apparent increase in the levels of these SOD mRNAs.
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Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum
TL;DR: Modelling the differential susceptibility to oxidative stress of both parasite strains elicited by the glucose/glucose oxidase system revealed that maintenance of intracellular glutathione in P. falciparum Dd2 appears to be able to sustain its intrACEllular glutATHione more efficiently than P. Falconerum 3D7.
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Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages.
Zita Krnajski,Tim-Wolf Gilberger,Tim-Wolf Gilberger,Rolf D. Walter,Alan F. Cowman,Sylke Müller,Sylke Müller +6 more
TL;DR: It is found that the co-transfected constructs form concatemeric structures prior to integration into the trxR gene locus, which is further supported by plasmid rescue followed by restriction analyses of the plasmids.