R
Romain Blasius
Publications - 10
Citations - 1272
Romain Blasius is an academic researcher. The author has contributed to research in topics: K562 cells & Curcumin. The author has an hindex of 9, co-authored 10 publications receiving 1212 citations.
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Journal ArticleDOI
Chemopreventive and therapeutic effects of curcumin.
Annelyse Duvoix,Romain Blasius,Sylvie Delhalle,Michael Schnekenburger,Franck Morceau,Estelle Henry,Mario Dicato,Marc Diederich +7 more
TL;DR: Curcumin is described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems capable of suppression, retardation or inversion of carcinogenesis.
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A Beginner's Guide to NF-κB Signaling Pathways
TL;DR: Advantages that can issue from various studies on nuclear factor κB are summarized, and a few compounds seem particularly promising.
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Inhibition of TNFα-induced activation of nuclear factor κB by kava (Piper methysticum) derivatives
Florence Folmer,Romain Blasius,Franck Morceau,Jioji N. Tabudravu,Mario Dicato,Marcel Jaspars,Marc Diederich +6 more
TL;DR: Insight is given into anti-inflammatory mechanisms triggered by traditionally used chemopreventive kava compounds used in traditional medicine against urinary tract infections and asthma.
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Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition.
Annelyse Duvoix,Sylvie Delhalle,Romain Blasius,Michael Schnekenburger,Franck Morceau,Marjorie Fougère,Estelle Henry,Marie-Madeleine Galteau,Mario Dicato,Marc Diederich +9 more
TL;DR: The ability of selected chemopreventive agents to decrease GSTP1-1 gene expression mechanisms and could thus contribute to reduce the incidence of glutathione related drug resistance in human leukemia.
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Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells
TL;DR: Curcumin treatment induced a decrease of nuclear STAT3, -5a and -5b, without affecting neitherSTAT1, nor the phosphorylation state of STAT1, -3 or -5 in the K562 cell line, indicating that curcumin is able to induce the cleavage of STAT5 into its dominant negative variants lacking the STAT5 C-terminal region.