Rosalba Siracusa

TL;DR: The current knowledge pertaining to astrocytes’ role in brain pathologies is described and the possibilities to target them as approach toward pharmacological therapies for neuro-pathologies are discussed.

TL;DR: A focus on the available knowledge about the NLRP3 inflammasome role in disorders with a high impact on public health and the balance between the activation of the harmful and beneficial inflammaome so that new therapies can be created for patients with these diseases is provided.

TL;DR: Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain, often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations in sleep and mood.

TL;DR: Hidrox® (HD) is subject to fewer regulations than traditional drugs to improve patients’ brain health and could represent a promising nutraceutical choice to prevent Parkinson’s disease.

TL;DR: These findings illustrate the superior anti-inflammatory action exerted by orally administered, micronized PEA-m and ultramicronizedPEA-um, versus that of nonmicronized PeaPure, in the rat paw carrageenan model of inflammatory pain.