R
Rosier M
Researcher at Rhône-Poulenc
Publications - 1
Citations - 1463
Rosier M is an academic researcher from Rhône-Poulenc. The author has contributed to research in topics: ABCA1 & Tangier disease. The author has an hindex of 1, co-authored 1 publications receiving 1430 citations.
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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
Stephan Rust,Rosier M,Harald Funke,Real J,Amoura Z,Piette Jc,Deleuze Jf,Brewer Hb,Nicolas Duverger,Patrice Denefle,Gerd Assmann +10 more
TL;DR: Tangier disease (TD) was first discovered nearly 40 years ago in two siblings living on Tangier Island This autosomal co-dominant condition is characterized in the homozygous state by the absence of HDL-cholesterol (HDL-C) from plasma, hepatosplenomegaly, peripheral neuropathy and frequently premature coronary artery disease (CAD).