H
Harald Funke
Researcher at University of Jena
Publications - 148
Citations - 7802
Harald Funke is an academic researcher from University of Jena. The author has contributed to research in topics: Apolipoprotein B & Cholesterol. The author has an hindex of 42, co-authored 147 publications receiving 7560 citations. Previous affiliations of Harald Funke include Roche Diagnostics & Hoffmann-La Roche.
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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
Stephan Rust,Rosier M,Harald Funke,Real J,Amoura Z,Piette Jc,Deleuze Jf,Brewer Hb,Nicolas Duverger,Patrice Denefle,Gerd Assmann +10 more
TL;DR: Tangier disease (TD) was first discovered nearly 40 years ago in two siblings living on Tangier Island This autosomal co-dominant condition is characterized in the homozygous state by the absence of HDL-cholesterol (HDL-C) from plasma, hepatosplenomegaly, peripheral neuropathy and frequently premature coronary artery disease (CAD).
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KCNE1 mutations cause jervell and Lange-Nielsen syndrome.
Eric Schulze-Bahr,Qing Wang,H. Wedekind,Wilhelm Haverkamp,Qiuyun Chen,Yaling Sun,Claudia Rubie,Marco Hordt,Jeffrey A. Towbin,Martin Borggrefe,Gerd Assmann,Xiangdong Qu,John C. Somberg,Günter Breithardt,Carlos Oberti,Carlos Oberti,Harald Funke +16 more
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Lipoprotein(a) is an independent risk factor for myocardial infarction at a young age.
TL;DR: The data suggest that an increased concentration of lipoprotein(a) constitutes an independent risk factor for early myocardial infarction and the concentrations of Lp (a) and LDL cholesterol (apolipoprotein B) in serum are under separate metabolic control.
Journal Article
The emergence of triglycerides as a significant independent risk factor in coronary artery disease
TL;DR: The Prospective Cardiovascular Münster (PROCAM) study showed that fasting levels of triglycerides were an independent risk factor for CHD events, irrespective of serum levels of high density lipoprotein cholesterol (HDL-C) or low density cholesterol (LDL-L), and that individuals with potentially atherogenic lipid profiles should be managed initially through the introduction of lifestyle changes.
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Correction: Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model
Marko Gröger,Knut Rennert,Benjamin Giszas,Elisabeth Weiß,Julia Dinger,Harald Funke,Michael Kiehntopf,Frank T. Peters,Amelie Lupp,Michael Bauer,Ralf A. Claus,Otmar Huber,Alexander S. Mosig +12 more
TL;DR: This corrects the article DOI: 10.1038/srep21868 to indicate that the author of the paper is a doctor of medicine rather than a scientist, as previously reported.